Cortex

Recent articles

Headshots of Karl Deisseroth, Peter Hegemann and Georg Nagel.

How Nobel Prize-winning optogenetics has revolutionized neuroscience

The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.

Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read
Mouse cortical organoid.

Hasty stem cells highlight potential limitation with cortical organoids

The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.

By Giorgia Guglielmi
22 September 2026 | 4 min read
Nerve fibers from the human graft in mouse brain.

Human brain organoids flourish in emptied mouse cortex

The chimeric mice could help untangle the biology of human brain development or conditions such as autism.

By Brianna Abbott
16 September 2026 | 6 min read
Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 5 min read

Alison Barth discovers how different neuron types contribute to cortical function

Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.

By Paul Middlebrooks
5 August 2026 | 1 min read
Research image of the association cortex.

Cortical territories compete in developmental space race

Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.

By Holly Barker
30 July 2026 | 5 min read
Brain scans showing sex-based activation differences.

Brain’s sex differences are subtle and contradictory, large MRI study finds

Sex-based behavioral differences do not match with variations in brain activation or structure in a study of almost 1,000 people.

By Lauren Schenkman
8 July 2026 | 5 min read
Research image of cursor movement from high gamma activity.

Recording warning: Common brain signal may be misunderstood

High gamma activity in electrophysiologic recordings reflects widespread neural activity, not merely local firing, as previously thought.

By Claudia López Lloreda
30 June 2026 | 5 min read

Cortical area remixes macaques’ knowledge blocks to solve new problems

When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.

By Lauren Schenkman
19 June 2026 | 0 min watch

Explore more from The Transmitter

Susana Carmona on the neurobiology of pregnancy

In a Q&A about her new book, “A Mother’s Brain,” Carmona shares key moments in her career that led her to study the neuroscience of motherhood and discusses some of the major questions the field still needs to address.

By Francisco J. Rivera Rosario
6 October 2026 | 8 min read
Cerebellar Purkinje cells.

Aging biomarkers in autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 5 October.

By Jill Adams
6 October 2026 | 2 min read
Davi Bock standing in front of a poster showing visualizations of connectomes.

Beyond wiring diagrams: Inside a $19 million effort to expand access to connectome technology

Davi Bock’s lab took the millions of images that led to the complete connectome of a fruit fly brain. Now he wants to apply “this high-throughput flashlight across all areas of biology.”

By Calli McMurray
6 October 2026 | 11 min read