Cortex

Recent articles

Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
A cortical neuron glows orange and red.

START method assembles brain’s wiring diagram by cell type

The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

By Holly Barker
31 October 2024 | 5 min read
Research image of tau proteins in the brains of people with Alzheimer’s disease.

Supersized version of Alzheimer’s protein avoids clumping in brain

“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

By Charles Q. Choi
16 August 2024 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
Research image of fetal macaque brains.

Brain patterning in utero may be implicated in autism, other conditions

Genes tied to several conditions are expressed in regions that control neural stem cell fate within the first few months post-conception.

By Chloe Williams
1 August 2024 | 6 min read
A marble bust of a face that is covered in real leaves.

Newly found circuit through visual cortex powers first look at faces

The superior colliculus, an evolutionarily ancient brain area responsible for eye movements, responds to faces before the canonical face areas do, a study of macaque monkeys suggests.

By Olivia Gieger
19 July 2024 | 5 min read
A photograph of Paul-Antoine Libourel.

At the end of the earth with Paul-Antoine Libourel

The French researcher’s accomplishments working with chinstrap penguins in the Antarctic highlight the importance of recording sleep in the wild.

By Yves Sciama
11 June 2024 | 18 min listen
Illustration of a yellow brain and a pink brain

Monkey studies throw wrench into decade-old idea about movement’s effect on visual cortex

Movements that boost activity in the visual cortex of mice have the opposite or no effect in marmosets and macaques, prompting questions about whether mice are a suitable model for the primate visual system.

By Angie Voyles Askham
20 February 2024 | 9 min read
Two hands hold a mouse.

Noisy brain may underlie some of autism’s sensory features

Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.

By Holly Barker
18 January 2024 | 6 min read
Research images of the human motor cortex

What happens when a histopathologist teams up with computational modelers?

Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.

By Mac Shine
11 December 2023 | 7 min read

Explore more from The Transmitter

Illustration of the outlines of several different animals—including a fish, an insect and a rabbit—each filled in with a different color and overlaid with abstract patterns, lines and shapes.

Premature declarations on animal consciousness hinder progress

Overstating the evidence in support of animal consciousness could impede efforts to develop more accurate ways of assessing it.

By Hakwan Lau
18 November 2024 | 5 min read
Research image of a portion of mouse brain.

Stress warps fear memories in multiple ways

Expanding the bounds of a fear memory or linking it to a neutral memory can shape a mouse’s fear response, two new studies show.

By Claudia López Lloreda
15 November 2024 | 5 min read
Illustration of overlapping silhouettes of two faces in profile facing a matrix of dots of various colors and sizes.

How to be a multidisciplinary neuroscientist

Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.

By Austin Coley
15 November 2024 | 5 min read