Nenad Sestan
Professor of neuroscience
Yale University
From this contributor
Helpful hurdles
Rapid progress in gene discovery and an emerging map of the molecular landscape of normal brain development are presenting unprecedented opportunities to unravel the biology of autism spectrum disorders, say Matthew State and Nenad Sestan.
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Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.

Targeting NMDA receptor subunit reverses fragile X traits in mice
The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.
Maternal infection’s link to autism may be a mirage
Family-linked factors explain most associations between maternal illness and autism, a study of 1.1 million Danish children finds.

Maternal infection’s link to autism may be a mirage
Family-linked factors explain most associations between maternal illness and autism, a study of 1.1 million Danish children finds.
2025 Brain Prize honors pair of cancer neuroscientists
Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.

2025 Brain Prize honors pair of cancer neuroscientists
Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.