Headshot of Mark Humphries.

Mark Humphries

Chair in computational neuroscience
University of Nottingham

Mark Humphries is a theorist, neuroscientist and writer.

His lab studies how neurons collectively encode information about the past, present and future to guide behavior. He authored the popular science book “The Spike: An Epic Journey Through the Brain in 2.1 Seconds” and writes extensively about the brain for a broad audience at Medium and elsewhere.

Humphries is chair in computational neuroscience at the University of Nottingham. He previously held a senior fellowship from the United Kingdom’s Medical Research Council at the University of Manchester. Before that, he had a three-year fellowship at Ecole Normale Superieure in Paris. He did his postdoctoral and Ph.D. training at the University of Sheffield.

https://humphries-lab.org/

Get alerts for essays by Mark Humphries in your inbox.

Subscribe to get notified every time a new essay is published.

Explore more from The Transmitter

Illustration of rolling dice.

Grant review needs reform. How about we add an element of chance?

A process that uses a lottery system saves time, reduces strategic resubmission and accepts that, above a quality threshold, luck has always played a part in science funding.

By Adrien Peyrache
25 September 2026 | 6 min read
Research diagram of gene expression.

Fly neurons carry molecular signatures of their origins

The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.

By Alissa de Chassey
25 September 2026 | 5 min read
Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read