Jacob Vorstman is associate professor of psychiatry at the University of Toronto and director of the Autism Research Unit at the Hospital for Sick Children in Canada. Initially, his research focused on the psychiatric and genetic aspects of the 22q11.2 deletion. After obtaining his Ph.D. in 2008, he broadened the scope from 22q11.2 deletion syndrome to the study of genotype-phenotype relations in neurodevelopmental conditions — in particular, autism, intellectual disability and schizophrenia. His ambition is to further insights into the genetic architecture underlying these conditions as well as to improve methods to measure the associated phenotypes.
Jacob Vorstman
Professor
The Hospital for Sick Children
From this contributor
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
By
Lauren Schenkman
15 August 2024 | 7 min read
How polygenic scores can improve predictions about autism, schizophrenia
Jacob Vorstman wants to help people who have rare mutations tied to autism, schizophrenia and other neurodevelopmental conditions set expectations about outcomes.
How polygenic scores can improve predictions about autism, schizophrenia
By
Angie Voyles Askham
19 January 2021 | 7 min read
Explore more from The Transmitter
AI can’t solve the brain without data that fit together
The brain's first foundation models exist because some areas of neuroscience did the slow work of developing and adopting standards to help integrate data. Artificial intelligence cannot do that work for us.
AI can’t solve the brain without data that fit together
The brain's first foundation models exist because some areas of neuroscience did the slow work of developing and adopting standards to help integrate data. Artificial intelligence cannot do that work for us.
By
Sean Hill
29 June 2026 | 8 min read
Queerying neuroscience: How legislation and institutions reframe LGBTQIA+ researchers’ careers
In honor of Pride Month, The Transmitter spoke with three researchers who surveyed hundreds of LGBTQIA+ neuroscientists to better understand how institutional support, harassment and policy intersect to shape their professional trajectories.
Queerying neuroscience: How legislation and institutions reframe LGBTQIA+ researchers’ careers
In honor of Pride Month, The Transmitter spoke with three researchers who surveyed hundreds of LGBTQIA+ neuroscientists to better understand how institutional support, harassment and policy intersect to shape their professional trajectories.
By
Paige Miranda
29 June 2026 | 0 min watch
Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion
The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.
Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion
The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.
By
Sarah Thau
26 June 2026 | 8 min read