Isabel Ruehl is a former editorial intern at Spectrum. She recently graduated from Columbia Journalism School and, before that, earned an M.Phil. in Health, Medicine and Society from Cambridge University in the United Kingdom.
Isabel Ruehl
Former news intern
Spectrum
From this contributor
‘Science working as it should’: Autism blood signature study earns open post-publication review
Shortly after the study’s publication, experts critiqued it on PubPeer and other online platforms.
‘Science working as it should’: Autism blood signature study earns open post-publication review
By
Isabel Ruehl
10 January 2023 | 5 min read
Whole-genome trove ties new genes, variants to autism
A massive update to the MSSNG dataset gives qualified researchers ready access to explore autism’s genetic architecture on a cloud-based platform.
Whole-genome trove ties new genes, variants to autism
By
Isabel Ruehl
12 December 2022 | 4 min read
Autism incidence in England varies by ethnicity, class, location
High rates of autism are linked to lower socioeconomic status and minority ethnic groups, according to the largest-ever autism incidence study.
Autism incidence in England varies by ethnicity, class, location
By
Isabel Ruehl
6 December 2022 | 5 min read
‘Assembloids’ lay bare autism-linked genes that hamper neuron development
The model enables the study of autism-linked genes at the earliest stages of neural development.
‘Assembloids’ lay bare autism-linked genes that hamper neuron development
By
Isabel Ruehl
30 November 2022 | 4 min read
Lab-grown ‘embryoids’ offer new window into gene-trait relationships
The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.
Lab-grown ‘embryoids’ offer new window into gene-trait relationships
By
Isabel Ruehl
26 October 2022 | 4 min read
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Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
Mitochondrial ‘landscape’ shifts across human brain
Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.
By
Claudia López Lloreda
25 April 2025 | 6 min read
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
By
Lauren Schenkman
24 April 2025 | 8 min read
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
By
Shane Liddelow
23 April 2025 | 6 min read