David Ledbetter is chief clinical officer of Dascena, a personalized medicine company.
David Ledbetter
Chief clinical officer
Dascena
From this contributor
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
There are no autism-specific genes, just brain genes
Developmental disorders should be viewed as continuum
Intellectual disability, autism, epilepsy and schizophrenia should be considered part of a spectrum of developmental brain dysfunction, says David Ledbetter.
Developmental disorders should be viewed as continuum
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Hasty stem cells highlight potential limitation with cortical organoids
The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.
Hasty stem cells highlight potential limitation with cortical organoids
The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.
Two populations of neurons, two effects on sociability; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.
Two populations of neurons, two effects on sociability; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.
Finding the Rett syndrome gene and ways to fix it
Kevin Mitchell talks with Huda Zoghbi about her work identifying the MECP2 gene, its role in the brain and therapies to address its dysfunction.
Finding the Rett syndrome gene and ways to fix it
Kevin Mitchell talks with Huda Zoghbi about her work identifying the MECP2 gene, its role in the brain and therapies to address its dysfunction.