David Ledbetter is chief clinical officer of Dascena, a personalized medicine company.
David Ledbetter
Chief clinical officer
Dascena
From this contributor
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
There are no autism-specific genes, just brain genes
By
David Ledbetter, Scott Myers
23 March 2021 | 5 min read
Developmental disorders should be viewed as continuum
Intellectual disability, autism, epilepsy and schizophrenia should be considered part of a spectrum of developmental brain dysfunction, says David Ledbetter.
Developmental disorders should be viewed as continuum
By
David Ledbetter
6 May 2013 | 3 min read
Explore more from The Transmitter
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.
Tom Griffiths describes how neural networks, logic and probability theory together explain cognition
In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.
By
Paul Middlebrooks
11 March 2026 | 100 min listen
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
By
Talia Lerner
11 March 2026 | 6 min read
Portfolio of SCN2A gene variants, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 9 March.
Portfolio of SCN2A gene variants, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 9 March.
By
Jill Adams
10 March 2026 | 2 min read