David Ledbetter is chief clinical officer of Dascena, a personalized medicine company.
David Ledbetter
Chief clinical officer
Dascena
From this contributor
There are no autism-specific genes, just brain genes
There is not yet a single example of a gene that, when mutated, increases the likelihood of autism but not of other neurodevelopmental conditions, including intellectual disability.
There are no autism-specific genes, just brain genes
By
David Ledbetter, Scott Myers
23 March 2021 | 5 min read
Developmental disorders should be viewed as continuum
Intellectual disability, autism, epilepsy and schizophrenia should be considered part of a spectrum of developmental brain dysfunction, says David Ledbetter.
Developmental disorders should be viewed as continuum
By
David Ledbetter
6 May 2013 | 3 min read
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This paper changed my life: John Tuthill reflects on the subjectivity of selfhood
Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biological odometer, and it inspired Tuthill to consider how other insects sense their own bodies.
This paper changed my life: John Tuthill reflects on the subjectivity of selfhood
Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biological odometer, and it inspired Tuthill to consider how other insects sense their own bodies.
By
John Tuthill
12 January 2026 | 7 min read
Some facial expressions are less reflexive than previously thought
A countenance such as a grimace activates many of the same cortical pathways as voluntary facial movements.
Some facial expressions are less reflexive than previously thought
A countenance such as a grimace activates many of the same cortical pathways as voluntary facial movements.
By
Natalia Mesa
8 January 2026 | 5 min read
Cracking the neural code for emotional states
Rather than act as a simple switchboard for innate behaviors, the hypothalamus encodes an animal's internal state, which influences behavior.
Cracking the neural code for emotional states
Rather than act as a simple switchboard for innate behaviors, the hypothalamus encodes an animal's internal state, which influences behavior.
By
Natalia Mesa
8 January 2026 | 8 min read