Headshot of Nicole Rust

Nicole Rust

Professor of psychology, University of Pennsylvania;
Contributing editor, The Transmitter

Nicole Rust is professor of psychology at the University of Pennsylvania in Philadelphia. Her research focuses on understanding the brain’s remarkable ability to remember the things we’ve seen and using that knowledge to develop new therapies to treat memory dysfunction. She is also writing a book on the types of understanding of the brain that will ultimately be required to treat neurological and psychiatric conditions. In it, she argues that effective progress in brain research will require ambitious and unprecedented multidisciplinary conversations of the type that will appear in The Transmitter.

Rust received her Ph.D. in neuroscience from New York University and completed her postdoctoral training at the Massachusetts Institute of Technology. She has been recognized by the Troland Research Award from the National Academy of Sciences, the McKnight Scholar Award, a CAREER Award from the National Science Foundation, a Sloan Research Fellowship, the Charles Ludwig Distinguished Teaching Award, and election to the Memory Disorders Research Society.

Get alerts for essays by Nicole Rust in your inbox.

Subscribe to get notified every time a new essay is published.

Explore more from The Transmitter

Mice playing, engaged in learning and memory: some of their brains are yellow, and some are red, matching a red and yellow legend that runs through the image to underscore both memory and learning.

This paper changed my life: A technical breakthrough for memory studies

In a 2007 Science paper, Mark Mayford and his colleagues found that some neurons activated during learning are also recruited during memory retrieval. Noelia Weisstaub shares how this study and others drove an era of great progress in tool development.

By Noelia Weisstaub
14 August 2026 | 5 min read

Early experience reshapes zebrafish retinal cells, alters behavior

The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.

By Siddhant Pusdekar
13 August 2026 | 0 min watch
Research image of expression of MEIS2 in PV interneurons.

Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions

Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.

By Claudia López Lloreda
12 August 2026 | 5 min read