Connectome

Recent articles

Research diagram of gene expression.

Fly neurons carry molecular signatures of their origins

The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.

By Alissa de Chassey
25 September 2026 | 5 min read
Illustration of brain taking shape.

Neuroscientists weigh in on White House proposal for ‘moonshot infrastructure’ for connectomics

A report from the Trump administration calls for a “new golden age” of science, in which the federal government supports mission-driven collaborations to deliver high returns on research investments.

By Sarah Thau
24 July 2026 | 4 min read

Long-sought walking circuit found in fruit flies

The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.

By Natalia Mesa
13 May 2026 | 0 min watch
Research image of lesion network mapping.

‘Overdue’ debate unfurls over neuroimaging method

After a January paper questioned the validity of an approach called lesion network mapping, its users are pressure testing their results.

By Angie Voyles Askham
17 April 2026 | 8 min read
Digital model of a fly next to a digital model of a nematode.

‘Digital sphinx’ raises questions about connectome models

The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

By Natalia Mesa
2 April 2026 | 5 min read
Researcher Russell Poldrack's face closeup, with a scanner seen out of focus behind him.

A brief history of precision self-scanning

When a researcher solved a logistical problem by going rogue, the idea proved remarkably infectious.

By Lauren Gravitz
21 January 2026 | 13 min read
Brain network maps creating using lesion network mapping.

Methodological flaw may upend network mapping tool

The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.

By Angie Voyles Askham
15 January 2026 | 7 min read

Can neuroscientists decode memories solely from a map of synaptic connections?

Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns.

By Paul Middlebrooks
17 December 2025 | 1 min read
A man with glasses reads from a paper with a graph-like pattern of peaks and valleys on it.

The buzziest neuroscience papers of 2023, 2024

The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations, and more.

By Calli McMurray, Francisco J. Rivera Rosario
15 November 2025 | 18 min read
A worm made of circuitry.

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read

Explore more from The Transmitter

Illustration of two cats jumping to opposite buildings in a city.

Is confidence a second thought—or part of the first one?

In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.

By Ariel Zylberberg
5 October 2026 | 6 min read
Illustration of a plate with a cherry in front of a computer server.

What AI can learn from hunger

To enhance AI safety, take a lesson from biological brains; a small set of wants maintains durable control over a much larger cognitive system.

By Anthony Zador
5 October 2026 | 6 min read

New projectome captures ‘complex beast’ of serotonin system in mice

The whole-brain map—the first of its kind in a vertebrate—identifies five distinct neuron groups.

By Madeline Shaw
2 October 2026 | 0 min watch