Connectivity

Recent articles

A cortical neuron glows orange and red.

START method assembles brain’s wiring diagram by cell type

The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

By Holly Barker
31 October 2024 | 5 min read
Research image of neurons in the fly’s ventral nerve cord.

New connectomes fly beyond the brain

Researchers are mapping the neurons in Drosophila’s ventral nerve cord, where the central nervous system meets the rest of the body.

By Laura Dattaro
26 July 2024 | 7 min read
Research image of a variety of brain atlases.

New ‘decoder’ tool translates functional neuroimaging terms across labs

The compendium of brain-parcellation atlases makes it possible to compare large-scale network data, which often involves different and overlapping network names.

By Holly Barker
23 July 2024 | 4 min read
A marble bust of a face that is covered in real leaves.

Newly found circuit through visual cortex powers first look at faces

The superior colliculus, an evolutionarily ancient brain area responsible for eye movements, responds to faces before the canonical face areas do, a study of macaque monkeys suggests.

By Olivia Gieger
19 July 2024 | 5 min read
Black-and-white research image of brain organoids.

Brain organoid size matches intensity of social problems in autistic people

Overgrown organoids could point to mechanisms underlying profound autism.

By Holly Barker
18 July 2024 | 5 min read
Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read
Research image of brain activity

Connectivity takes U-turn in people with rare autism-linked mutations

Patterns of brain connectivity shift during puberty in people with deletion of the 22q11.2 chromosomal region.

By Holly Barker
30 May 2024 | 4 min read

Drafting a ‘dysfunctome’: Faulty connections to subthalamic nucleus characterize disparate brain disorders

Different circuits between the millimeters-wide structure and the cortex go awry in Tourette syndrome, obsessive-compulsive disorder, dystonia and Parkinson’s disease, a new study of human brain scans suggests.

By Elissa Welle
16 April 2024 | 5 min read
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
Two hands hold a mouse.

Noisy brain may underlie some of autism’s sensory features

Random fluctuations in neuronal activity are more variable in a fragile X mouse model than in wildtype mice.

By Holly Barker
18 January 2024 | 6 min read

Explore more from The Transmitter

Research image of brain organoids with astroglia formation represented in green.

Personalized medicine; astroglia organoids; fast track for fragile X drug

Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.

By Jill Adams
21 January 2025 | 2 min read
Illustration of clinicians, a pill bottle, a speech bubble and shadowy figures.

Neuroscientists need to do better at explaining basic mental health research

The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.

By Omar Abubaker, Karla Kaun, Eric J. Nestler
21 January 2025 | 7 min read
Grid of human brain scans.

Dose, scan, repeat: Tracking the neurological effects of oral contraceptives

We know little about how the brain responds to oral contraceptives, despite their widespread use. I am committed to changing that: I scanned my brain 75 times over the course of a year and plan to make my data openly available.

By Carina Heller
20 January 2025 | 7 min read