Computational neuroscience

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This series examines the latest advances and insights on the intersection between neuroscience and AI.

Illustration of pixelated AI models.

Models at the speed of thought: How AI coding is reshaping theoretical neuroscience

Agentic coding makes it possible to specify a neuroscience model in hours instead of months. Seven neuroscientists weigh in on what that tectonic change may bring to the field.

By Brian DePasquale
16 June 2026 | 17 min read
Neural networks illustration.

This paper changed my life: Appreciating John Hopfield’s brilliant neural network

In a 1982 paper, the Nobel laureate created his namesake recurrent neural network—work that taught Maria Geffen to always ground research questions in biology.

By Maria Geffen
15 May 2026 | 5 min read
Illustration of a sheet of paper with a topography map-like pattern on it.

Why neural foundation models work, and what they might—and might not—teach us about the brain

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?

By Juan Gallego
13 April 2026 | 8 min read
A fragmenting cube hovers over a person reading a book.

Error equation predicts brain’s ability to generalize

Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests.

By Natalia Mesa
10 April 2026 | 5 min read

Romain Brette reveals fundamental flaws in commonly assumed neuroscience concepts

His new book, “The Brain, In Theory,” offers alternatives to many of the computer science frameworks currently driving theoretical neuroscience.

By Paul Middlebrooks
8 April 2026 | 131 min listen

Explore more from The Transmitter

Are computational complexity principles relevant for explaining brain activity?

Cristopher Moore discusses the nature of computation and whether we should think of neural activity as computing.

By Paul Middlebrooks
17 June 2026 | 1 min read
Illustration of cells converting from fibroblasts to myoblasts.

This paper changed my life: Learning the molecular rules of cell identity

A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.

By Ardem Patapoutian
17 June 2026 | 6 min read

Leucovorin saga, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 15 June.

By Jill Adams
16 June 2026 | 2 min read