Computational neuroscience

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This series examines the latest advances and insights on the intersection between neuroscience and AI.

Illustration of a sheet of paper with a topography map-like pattern on it.

Why neural foundation models work, and what they might—and might not—teach us about the brain

These models can partly generalize across species, brain regions and tasks, suggesting that a set of machine-learnable rules govern neural population activity. But will we be able to understand them?

By Juan Gallego
13 April 2026 | 8 min read
A fragmenting cube hovers over a person reading a book.

Error equation predicts brain’s ability to generalize

Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests.

By Natalia Mesa
10 April 2026 | 5 min read

Romain Brette reveals fundamental flaws in commonly assumed neuroscience concepts

His new book, “The Brain, In Theory,” offers alternatives to many of the computer science frameworks currently driving theoretical neuroscience.

By Paul Middlebrooks
8 April 2026 | 131 min listen
Book cover of The Brain, In Theory by Romain Brette.

‘The Brain, In Theory,’ an excerpt

In his new book, Brette pushes back against theories that describe the brain as a “biological computer.” In this excerpt from Chapter 4, he challenges equating brain evolution with programming, and the universality of neural network models.

By Romain Brette
7 April 2026 | 5 min read
Kieth Hengen looks through a small window, aligning his face with a fancy moustache sticker and rolling his eyes comically to the side.

Computational neuroscientist Keith Hengen explains his work through illustrations

The images help him communicate the “big-picture ideas” behind the mathematical principles of neuronal networks.

By Helena Kudiabor
7 April 2026 | 4 min read

Explore more from The Transmitter

California sea hare.

New study questions role of persistent gene activity in memory maintenance

An experiment in sea slugs suggests transcriptional changes might fade after 24 hours.

By Siddhant Pusdekar
28 April 2026 | 4 min read

Tracking health in autistic adults, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 27 April.

By Jill Adams
28 April 2026 | 2 min read
Illustration of two planet-like spheres orbiting one another.

Can AI do neuroscience without understanding?

Prediction without understanding sustained astronomy through a thousand years of epicycles. Artificial intelligence is now offering neuroscience the same deal.

By Anthony Zador
27 April 2026 | 6 min read