Clinical trials

Recent articles

Illustration of hands holding cash.

Private initiative makes ‘historic’ investment in autism research

Aligning Research to Impact Autism has committed more than $450 million to build a new multidisciplinary research network to uncover the roots of profound autism and develop treatments.

By Madeline Shaw
13 October 2026 | 4 min read
Burke Neurological Institute.

Exclusive: Brain and spinal cord institute halts research, citing funding problems

The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.

By Lauren Schenkman
4 June 2026 | 5 min read
A stack of paper topped by bits of shredded paper.

NIH scraps policy that classified basic research in people as clinical trials

The policy aimed to increase the transparency of research in humans but created “a bureaucratic nightmare” for basic neuroscientists.

By Calli McMurray
3 February 2026 | 6 min read
Collage of digestive-system organs, the brain and various shapes and figures.

Going against the gut: Q&A with Kevin Mitchell on the autism-microbiome theory

A new review of 15 years of studies on the connection between the microbiome and autism reveals widespread statistical and conceptual errors.

By Lauren Schenkman
13 November 2025 | 7 min read
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 6 min read
Bag of umbilical cord blood.

Why hype for autism stem cell therapies continues despite dead ends

After numerous tests, there is still no evidence that these experimental treatments help, so now is not the time to expand access to them.

By Paul Knoepfler
22 August 2025 | 5 min read
A clinician holds a clipboard while someone else sits on a couch.

Expediting clinical trials for profound autism: Q&A with Matthew State

Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

By Lauren Schenkman
24 April 2025 | 8 min read
Photograph of a syringe.

What’s next for brain-directed gene therapy after death in Neurogene trial

The incident highlights that viral vectors can trigger deadly immune responses even when delivered directly to the nervous system.

By Calli McMurray
26 November 2024 | 6 min read
Bret Rutherford.

Former Columbia University psychiatrist committed research misconduct, says federal watchdog

Bret Rutherford, whose research was halted following a suicide in a clinical trial, falsely reported participant eligibility, according to the U.S. Office of Research Integrity.

By Brendan Borrell, Ellie Kincaid
8 October 2024 | 3 min read
Illustration of researchers talking to laypeople amidst strands of DNA.

Building an autism research registry: Q&A with Tony Charman

A purpose-built database of participants who have shared genomic and behavioral data could give clinical trials a boost, Charman says.

By Cathleen O’Grady
25 July 2024 | 8 min read

Explore more from The Transmitter

Brain Flows book cover

‘Brain Flows: How Network Dynamics Compose the Human Mind,’ an excerpt

In his new book, published today, Michael W. Cole examines how the movement of neuronal activity between neuronal populations shapes free will, intelligence and creativity. In this excerpt from Chapter 1, Cole explores why activity flows could unify efforts to map brain functions and connectivity.

By Michael W. Cole
3 November 2026 | 9 min read
Research image showing copy number variants in prenatal cortical neurons.

Prenatal pruning of neurons with copy number variants; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 2 November.

By Jill Adams
3 November 2026 | 2 min read

New Stanford initiative aims to build digital twin of human brain

The effort, funded by private donors, seeks to train the model on a trove of MRI and magnetoencephalography data that scientists plan to collect over the next five years—but questions about its scientific utility and feasibility remain.

By Natalia Mesa
2 November 2026 | 0 min watch