Chromatin
Recent articles
Many autism-linked proteins influence hair-like cilia on human brain cells
The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.
Many autism-linked proteins influence hair-like cilia on human brain cells
The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Vast diversity of human brain cell types revealed in trove of new datasets
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
Vast diversity of human brain cell types revealed in trove of new datasets
The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Change of heart and mind: Autism’s ties to cardiac defects
Children with congenital heart disease have an increased likelihood of autism. Why?
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
Autism’s ties to the cell skeleton
Many genes related to the condition play a role in the internal scaffolding of cells, and cytoskeletal disruptions can affect neurodevelopment and behavior.
To repair DNA, neurons harness autism-linked proteins
The proteins are part of a newly discovered complex that mends genetic damage exclusively in neurons.
To repair DNA, neurons harness autism-linked proteins
The proteins are part of a newly discovered complex that mends genetic damage exclusively in neurons.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Flexible genomic architecture undergoes major redesigns during cerebellum development
A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.
Flexible genomic architecture undergoes major redesigns during cerebellum development
A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.
Explore more from The Transmitter
ABCD Study omits gender-identity data from latest release
The removal counteracts the goals of the longitudinal study by “pretending that some aspects of adolescent brain development don’t exist,” says sex differences researcher Nicola Grissom.
ABCD Study omits gender-identity data from latest release
The removal counteracts the goals of the longitudinal study by “pretending that some aspects of adolescent brain development don’t exist,” says sex differences researcher Nicola Grissom.
Neuropeptides reprogram social roles in leafcutter ants
The mechanisms that control the labor roles of ants may also be conserved in naked mole rats, a new study shows.
Neuropeptides reprogram social roles in leafcutter ants
The mechanisms that control the labor roles of ants may also be conserved in naked mole rats, a new study shows.
Perspectives from the field: Opinions in autism research
This collection of Spectrum articles from the past 12 months highlights expert perspectives on autism’s heritability and its link to biological sex, the value of transdiagnostic frameworks, and the field’s future, among other topics.
Perspectives from the field: Opinions in autism research
This collection of Spectrum articles from the past 12 months highlights expert perspectives on autism’s heritability and its link to biological sex, the value of transdiagnostic frameworks, and the field’s future, among other topics.