Cellular neuroscience
Recent articles
Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.
This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.
Astrocytes star in memory storage, recall
The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.

Astrocytes star in memory storage, recall
The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.
What are mechanisms? Unpacking the term is key to progress in neuroscience
Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.

What are mechanisms? Unpacking the term is key to progress in neuroscience
Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.
Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.

Supersized version of Alzheimer’s protein avoids clumping in brain
“Big tau” may explain why some brain regions, such as the cerebellum and brainstem, are largely spared from neurodegeneration, even though tau is expressed throughout the nervous system.
Is it time to worry about brain chimeras?
Brains made of neurons from two species raise new concerns.

Is it time to worry about brain chimeras?
Brains made of neurons from two species raise new concerns.
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Widely used calcium imaging protocol can lead to spurious results, new paper cautions
The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.
Knowledge graphs can help make sense of the flood of cell-type data
These tools, widely used in the technology industry, could provide a foundation for the study of brain circuits.

Knowledge graphs can help make sense of the flood of cell-type data
These tools, widely used in the technology industry, could provide a foundation for the study of brain circuits.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.

Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
New genetic tools usher amphibian neuroscience research into modern age
Harmless viruses that ferry genes into the brain cells of rodents and monkeys also work in frogs, newts and axolotls, according to two new preprints.

New genetic tools usher amphibian neuroscience research into modern age
Harmless viruses that ferry genes into the brain cells of rodents and monkeys also work in frogs, newts and axolotls, according to two new preprints.
Explore more from The Transmitter
Who funds your basic neuroscience research? Help The Transmitter compile a list of funding sources
We want to hear from you about the sources of funding for your research.
Who funds your basic neuroscience research? Help The Transmitter compile a list of funding sources
We want to hear from you about the sources of funding for your research.
The future of neuroscience research at U.S. minority-serving institutions is in danger
Cuts to federally funded programs present an existential crisis for the University of Puerto Rico’s rich neuroscience community and for research at minority-serving institutions everywhere.

The future of neuroscience research at U.S. minority-serving institutions is in danger
Cuts to federally funded programs present an existential crisis for the University of Puerto Rico’s rich neuroscience community and for research at minority-serving institutions everywhere.
Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’
The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.

Unexpected astrocyte gene flips image of brain’s ‘stalwart sentinels’
The genetic marker upends the accepted orientation of non-star-like astrocytes in the glia limitans superficialis.