Cell types
Recent articles
Five-year-old human brain organoids aged on schedule
The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.
Five-year-old human brain organoids aged on schedule
The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.
Textbook model of hippocampus’s role in memory may need updating
The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Liset de la Prida explains how neuron subtypes may control the activity of large neural populations, from manifolds to ripples
De la Prida's work analyzing the varieties of sharp wave ripples in the hippocampus led to her discovery that specific types of neurons control the properties of neural manifolds.
Liset de la Prida explains how neuron subtypes may control the activity of large neural populations, from manifolds to ripples
De la Prida's work analyzing the varieties of sharp wave ripples in the hippocampus led to her discovery that specific types of neurons control the properties of neural manifolds.
From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function
Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.
From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function
Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.
‘Tour de force’ study flags fount of interneurons in human brain
The newly discovered cell type might point to the origins of the inhibitory imbalance linked to autism and other conditions.
‘Tour de force’ study flags fount of interneurons in human brain
The newly discovered cell type might point to the origins of the inhibitory imbalance linked to autism and other conditions.
‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons
The atlas also offers up molecular and cellular targets for new pain therapies.
‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons
The atlas also offers up molecular and cellular targets for new pain therapies.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Explore more from The Transmitter
The term ‘model organism’ should be reserved for biological systems
By referring to artificial neural networks as model organisms, we run the risk of distorting funding priorities and disregard the explanatory power of a shared evolutionary history across biological organisms.
The term ‘model organism’ should be reserved for biological systems
By referring to artificial neural networks as model organisms, we run the risk of distorting funding priorities and disregard the explanatory power of a shared evolutionary history across biological organisms.
New phase of BRAIN Initiative spawns basal ganglia ‘parts list’
With a standardized cell naming system and infrastructure for data collection and analysis, the basal ganglia project sets the stage for a whole-brain primate atlas.
New phase of BRAIN Initiative spawns basal ganglia ‘parts list’
With a standardized cell naming system and infrastructure for data collection and analysis, the basal ganglia project sets the stage for a whole-brain primate atlas.
Machine-learning model spots autism-linked variants that scramble splicing
The model provides a way to investigate genetic variation in regions of the genome whose functions have been difficult to interpret.
Machine-learning model spots autism-linked variants that scramble splicing
The model provides a way to investigate genetic variation in regions of the genome whose functions have been difficult to interpret.