Cell types
Recent articles
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
Allen Institute sets sights on treatments for five brain diseases
The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Gene activity in human cortex shows striking sex differences
The results mark a “dramatic shift” in how neuroscientists think about sex differences, and they may help explain sex biases in certain neurodegenerative and neurodevelopmental conditions.
Liset de la Prida explains how neuron subtypes may control the activity of large neural populations, from manifolds to ripples
De la Prida's work analyzing the varieties of sharp wave ripples in the hippocampus led to her discovery that specific types of neurons control the properties of neural manifolds.
Liset de la Prida explains how neuron subtypes may control the activity of large neural populations, from manifolds to ripples
De la Prida's work analyzing the varieties of sharp wave ripples in the hippocampus led to her discovery that specific types of neurons control the properties of neural manifolds.
From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function
Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.
From genes to dynamics: Examining brain cell types in action may reveal the logic of brain function
Defining brain cell types is no longer a matter of classification alone, but of embedding their genetic identities within the dynamical organization of population activity.
‘Tour de force’ study flags fount of interneurons in human brain
The newly discovered cell type might point to the origins of the inhibitory imbalance linked to autism and other conditions.
‘Tour de force’ study flags fount of interneurons in human brain
The newly discovered cell type might point to the origins of the inhibitory imbalance linked to autism and other conditions.
‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons
The atlas also offers up molecular and cellular targets for new pain therapies.
‘Unprecedented’ dorsal root ganglion atlas captures 22 types of human sensory neurons
The atlas also offers up molecular and cellular targets for new pain therapies.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Among brain changes studied in autism, spotlight shifts to subcortex
The striatum and thalamus are more likely than the cerebral cortex to express autism variants or bear transcriptional changes, two unpublished studies find.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Constellation of studies charts brain development, offers ‘dramatic revision’
The atlases could pinpoint pathways that determine the fate of cells linked to neurodevelopmental conditions.
Nature retracts paper on novel brain cell type against authors’ wishes
A 2022 paper was retracted after an independent team of researchers reanalyzed the data and questioned its validity.
Nature retracts paper on novel brain cell type against authors’ wishes
A 2022 paper was retracted after an independent team of researchers reanalyzed the data and questioned its validity.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind
Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.
Explore more from The Transmitter
IQ’s link to brain structure, function in children may be a mirage
A child’s socioeconomic status, screen time and amount of sleep all show stronger associations with measures of brain structure and function, according to an imaging study of nearly 12,000 9- to 10-year-olds.
IQ’s link to brain structure, function in children may be a mirage
A child’s socioeconomic status, screen time and amount of sleep all show stronger associations with measures of brain structure and function, according to an imaging study of nearly 12,000 9- to 10-year-olds.
When autistic kids grow up, Chapter 2: “You need to go to college”
With just a high school equivalency degree and struggling as a single mother, Tempest McDonald is forced to shift her priorities.
When autistic kids grow up, Chapter 2: “You need to go to college”
With just a high school equivalency degree and struggling as a single mother, Tempest McDonald is forced to shift her priorities.
Noncoding RNA sways core autism traits in mice
Small deletions in an X-linked RNA alter social and repetitive behaviors in male mice without broadly affecting learning or memory.
Noncoding RNA sways core autism traits in mice
Small deletions in an X-linked RNA alter social and repetitive behaviors in male mice without broadly affecting learning or memory.