C. elegans

Recent articles

A group of researchers reading while institutions crumble in the background, and giant mice appear on the horizon.

The Transmitter’s favorite essays of 2025

Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.

By The Transmitter
24 December 2025 | 2 min read
A worm made of circuitry.

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read
Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans. 

By Holly Barker
29 August 2025 | 7 min read
Artistic illustration of a neural manifold.

Neural population-based approaches have opened new windows into neural computations and behavior

Neural manifold properties can help us understand how animal brains deal with complex information, execute flexible behaviors and reuse common computations.

By Matthew Perich
4 August 2025 | 7 min read
Still from research video displaying wiring map of a fruit fly's brain.

Standout neuroscience news in 2023

Did you miss any of our favorite stories from the past year? Revisit them here.

By The Transmitter
27 December 2023 | 3 min read
Research image of neurons

Plugging invisible gaps in the synaptic connectome

Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.

By Elissa Welle
6 December 2023 | 6 min read

Controlling neurons with ultrasound: Q&A with Sreekanth Chalasani

The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.

By Niko McCarty
1 March 2022 | 0 min watch
Photograph of a researcher holding a zebra finch.

Fish, frogs, flies and other fauna in scientific firsts

Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.

By Sarah DeWeerdt
8 September 2021 | 4 min read
A lighthearted, colorful, chaotic lab scene with fruit flies flying in formation, worms peeking out of piles of dirt and zebrafish spilling out of beakers.

What studying worms, flies and fish says about autism

Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.

By Sarah DeWeerdt
8 September 2021 | 18 min read

Stimulant restores cell signaling, eases behavior issues in animals missing autism gene

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

By Peter Hess
28 May 2021 | 4 min read

Explore more from The Transmitter

Illustrated collage of a monkey profile, a gloved hand holding a vaccine syringe touching an outline of the United States with two primates sitting near it, a strand of DNA, and flags of the United States and China in the background.

U.S. national primate research centers face an uncertain future

The facilities were meant to last 100 years. Four decades shy of that mark, amid flatlined funds and mounting political pressure, their directors are trying to find a path forward.

By Calli McMurray
9 October 2026 | 12 min read
Reflections of primates in lab equipment (bottom left: Rhesus macaque, top left: Pig-tailed macaque, bottom right: Crab-eating macaque. top right: Marmoset

What if nonhuman primate research goes away?

As the U.S. government takes steps to stop using nonhuman primates in research, The Transmitter investigates what that shift could mean for neuroscience.

By The Transmitter
9 October 2026 | 2 min read
Illustration of primate hands interacting with objects of cognitive tests.

The neuroscience questions that need nonhuman primates

The Transmitter asked 17 neuroscientists what questions might remain unanswered if support for nonhuman primate research continues to decline.

By Alissa de Chassey
9 October 2026 | 10 min read