C. elegans
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The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
Neural population-based approaches have opened new windows into neural computations and behavior
Neural manifold properties can help us understand how animal brains deal with complex information, execute flexible behaviors and reuse common computations.
Neural population-based approaches have opened new windows into neural computations and behavior
Neural manifold properties can help us understand how animal brains deal with complex information, execute flexible behaviors and reuse common computations.
Standout neuroscience news in 2023
Did you miss any of our favorite stories from the past year? Revisit them here.
Standout neuroscience news in 2023
Did you miss any of our favorite stories from the past year? Revisit them here.
Plugging invisible gaps in the synaptic connectome
Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.
Plugging invisible gaps in the synaptic connectome
Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.
Controlling neurons with ultrasound: Q&A with Sreekanth Chalasani
The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.
Controlling neurons with ultrasound: Q&A with Sreekanth Chalasani
The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.
Fish, frogs, flies and other fauna in scientific firsts
Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.
Fish, frogs, flies and other fauna in scientific firsts
Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.
What studying worms, flies and fish says about autism
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
What studying worms, flies and fish says about autism
Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.
Stimulant restores cell signaling, eases behavior issues in animals missing autism gene
Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.
Stimulant restores cell signaling, eases behavior issues in animals missing autism gene
Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.
Explore more from The Transmitter
Early experience reshapes zebrafish retinal cells, alters behavior
The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.
Early experience reshapes zebrafish retinal cells, alters behavior
The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
Neuropsychiatric MRI brain signatures fail reproducibility test
Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.
Neuropsychiatric MRI brain signatures fail reproducibility test
Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.