C. elegans

Recent articles

A group of researchers reading while institutions crumble in the background, and giant mice appear on the horizon.

The Transmitter’s favorite essays of 2025

Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.

By The Transmitter
24 December 2025 | 2 min read
A worm made of circuitry.

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read
Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans

By Holly Barker
29 August 2025 | 7 min read
Artistic illustration of a neural manifold.

Neural population-based approaches have opened new windows into neural computations and behavior

Neural manifold properties can help us understand how animal brains deal with complex information, execute flexible behaviors and reuse common computations.

By Matthew Perich
4 August 2025 | 7 min read
Still from research video displaying wiring map of a fruit fly's brain.

Standout neuroscience news in 2023

Did you miss any of our favorite stories from the past year? Revisit them here.

By The Transmitter
27 December 2023 | 3 min read
Research image of neurons

Plugging invisible gaps in the synaptic connectome

Two new maps of the roundworm nervous system detail how neurons communicate with short proteins called neuropeptides outside synapses.

By Elissa Welle
6 December 2023 | 6 min read

Controlling neurons with ultrasound: Q&A with Sreekanth Chalasani

The new method, called sonogenetics, noninvasively manipulates neural circuits in mice.

By Niko McCarty
1 March 2022 | 7 min read
Photograph of a researcher holding a zebra finch.

Fish, frogs, flies and other fauna in scientific firsts

Over the past century, scientists have used a variety of animal models to advance their understanding of the developing brain and autism.

By Sarah DeWeerdt
8 September 2021 | 4 min read
A lighthearted, colorful, chaotic lab scene with fruit flies flying in formation, worms peeking out of piles of dirt and zebrafish spilling out of beakers.

What studying worms, flies and fish says about autism

Researchers are increasingly turning to simple animals to learn about autism biology and find leads for new drugs.

By Sarah DeWeerdt
8 September 2021 | 18 min read

Stimulant restores cell signaling, eases behavior issues in animals missing autism gene

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

By Peter Hess
28 May 2021 | 4 min read

Explore more from The Transmitter

A fragmenting cube hovers over a person reading a book.

Error equation predicts brain’s ability to generalize

Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests.

By Natalia Mesa
10 April 2026 | 5 min read
A large, abstract shape flows out of a small box.

Embrace complexity to improve the translatability of basic neuroscience

Researchers must learn to view heterogeneity as an essential feature of the systems they study and a central consideration in experimental design, not a variable to control for or reduce.

By Linda Douw, Klaus Eyer, Lara Keuck
9 April 2026 | 5 min read

Romain Brette reveals fundamental flaws in commonly assumed neuroscience concepts

His new book, “The Brain, In Theory,” offers alternatives to many of the computer science frameworks currently driving theoretical neuroscience.

By Paul Middlebrooks
8 April 2026 | 131 min listen