Brain Inspired

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This podcast, hosted by Paul Middlebrooks, features in-depth conversations with neuroscientists studying natural and artificial intelligence, philosophy, consciousness and other related areas.

Juan Gallego discusses how manifolds are transforming our understanding of the coordination of neuronal population activity

A wealth of evidence supports the view that neural manifolds are real and useful, Gallego says, even if they may not completely solve the age-old mind-body problem.

By Paul Middlebrooks
25 March 2026 | 121 min listen

Tom Griffiths describes how neural networks, logic and probability theory together explain cognition

In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.

By Paul Middlebrooks
11 March 2026 | 100 min listen

Three ecological psychologists on the right and wrong ways to use the field’s principles in neuroscience

Matthieu de Wit, Luis H. Favela and Vicente Raja weigh in on the recent trend of neuroscientists importing concepts from ecological psychology, the study of how an organism’s interactions with its environment explain perception and action.

By Paul Middlebrooks
25 February 2026 | 1 min read

Modern AI is simply no match for the complexity likely required for harboring consciousness, says Jaan Aru

He argues that our brain’s computations are of a completely different nature than any artificial intelligence because they take place across many spatial and temporal scales and are inextricably entwined with biological materials.

By Paul Middlebrooks
11 February 2026 | 1 min read

Michael Shadlen explains how theory of mind ushers nonconscious thoughts into consciousness

All of our thoughts, mostly nonconscious, are interrogations of the world, Shadlen says. The opportunity to report our answers to ourselves or others brings a thought into conscious awareness.

By Paul Middlebrooks
28 January 2026 | 1 min read

Tomaso Poggio on his quest for theories to explain the fundamental learning abilities of brains and machines

Thus far, engineering has outpaced theory in the science of intelligence. But Poggio is hopeful that theories can catch up.

By Paul Middlebrooks
14 January 2026 | 1 min read

Alex Maier argues that a scientific explanation of consciousness requires grounding in formalized mathematics

When it comes to discovering laws of nature for consciousness similar to those in physics, Maier argues that integrated information theory is the only game in town.

By Paul Middlebrooks
7 January 2026 | 1 min read

Can neuroscientists decode memories solely from a map of synaptic connections?

Five experts discuss the progress, possibilities and hurdles of decoding a “nontrivial” memory from an organism just by analyzing its brain connectivity patterns.

By Paul Middlebrooks
17 December 2025 | 1 min read

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read

Does AI understand what it produces? Henk de Regt explores how we might assess understanding in machines and humans

Building on his philosophy of how scientists understand what they work on, de Regt is extending his approach to test understanding in machines.

By Paul Middlebrooks
19 November 2025 | 1 min read

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Neuroscience conference policy draws confusion, apology

NeurIPS organizers apologized and altered course after issuing a policy that barred submissions from researchers at U.S.-government-sanctioned institutions.

By Dalmeet Singh Chawla
27 March 2026 | 5 min read
Assembloids in a petri dish.

Funding for animal research alternatives reaches ‘inflection point’

The United States and Europe are dedicating hundreds of millions of dollars in funding to advance novel alternative methods, but not all neuroscientists see this as a positive step.

By Claudia López Lloreda
26 March 2026 | 4 min read
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‘Friction-maxxing’ in school: Students should read primary literature, not AI summaries

Trainees need to learn how to identify a neuroscience paper’s major takeaways and integrate them into their understanding. This skill doesn’t come from outsourcing the work to large language models.

By Nora Bradford
26 March 2026 | 5 min read