Big data

Recent articles

Illustration of hands organizing objects of various shapes and sizes.

Simply making data publicly available isn’t enough. We need to make it easy — that requires community buy-in.

I helped create a standard to make it easy to upload, analyze and compare functional MRI data. An ecosystem of tools has since grown up around it, boosting reproducibility and speeding up research.

By Russell Poldrack
17 January 2024 | 7 min read

Explore more from The Transmitter

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read