Astrocytes

Recent articles

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
Research image of astrocytes in red activating alongside neurons in green in response to specific fear memories in mice.

Astrocytes star in memory storage, recall

The cells, long cast as support players in memory research, can activate or disrupt fear memories, according to a new study.

By Angie Voyles Askham
6 November 2024 | 5 min read
A research image showing astrocytes and neurons

‘SNAP’ dance of astrocytes and neurons falls out of step with age, disease

The findings add to growing evidence that astrocytes are star players in cognition.

By Laura Dattaro
6 March 2024 | 6 min read
Image of excitatory synapses in mouse brains.

Dispute erupts over role of sticky proteins in astrocytes

But multiple independent researchers say they are not convinced by its results, which fail to confirm high-profile findings from 2017.

By Lauren Schenkman
10 July 2023 | 9 min listen
Research image of gene-edited mouse liver cells compared to controls.

Latest ‘prime-editing’ tools tackle delivery, safety issues

The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.

By Charles Q. Choi
27 June 2023 | 5 min read
Research image of neurons and astrocytes.

Astrocytes fuel erratic firing in fragile X neurons

A shift in astrocyte secretions may explain the atypical firing patterns of neurons derived from people with fragile X syndrome.

By Lauren Schenkman
10 May 2023 | 5 min read
Autism researcher Veronica Martinez Cereno holds a brain in her lab.

Beyond the bench: At school with Verónica Martínez Cerdeño

Spectrum caught up with the University of California, Davis professor about her passion for volunteering in underserved schools, birding and fossil-hunting.

By Lauren Schenkman
1 May 2023 | 6 min read
Image of organoids modeling CDKL5 deficiency disorder.

Organoids identify potential therapies, circuit flaws for autism-linked syndromes

Brain cell clusters serve as drug screens and reveal connectivity differences for autism-linked conditions, two new models show.

By Peter Hess
21 November 2022 | 3 min read
Single astrocyte on black background.

Mouse studies cast astrocytes as stars of sensory perception

Data from two separate research teams suggest the cells are key to sensory hypersensitivity in fragile X syndrome.

By Sarah DeWeerdt
13 November 2022 | 4 min read
six images of astrocytes

How star cells’ secretions may stunt neurons: Q&A with Nicola Allen

Non-neuronal brain cells called astrocytes secrete proteins that seem to hamper the growth of neurons in people with autism-related syndromes. These proteins could be new drug targets, Allen says.

By Lauren Schenkman
26 September 2022 | 7 min read

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Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read
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David Krakauer reflects on the foundations and future of complexity science

In his book “The Complex World,” Krakauer explores how complexity science developed, from its early roots to the four pillars that now define it—entropy, evolution, dynamics and computation.

By Paul Middlebrooks
14 January 2025 | 106 min listen