ASHG 2019

Recent articles

RNA, transcription

Antidote to ‘poison’ DNA may treat lethal form of epilepsy

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

By Nicholette Zeliadt
26 August 2020 | 3 min read

Brain ‘organoids’ point to new drug target for fragile X syndrome

New findings hint at why drugs that work in mouse models of fragile X syndrome have not been effective in people.

By Nicholette Zeliadt
18 October 2019 | 3 min read
Illustration of a DNA strand.

Massive project doubles list of genes tied to autism

The largest analysis of sequences from autistic people and their families implicates 184 genes in the condition — nearly doubling the previous estimate.

By Nicholette Zeliadt
17 October 2019 | 3 min read

Explore more from The Transmitter

Alison Barth discovers how different neuron types contribute to cortical function

Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.

By Paul Middlebrooks
5 August 2026 | 1 min read
Mouse muscle cells.

Virus-like particles deliver gene-editing tools into Duchenne mouse model

The approach uses a protein found in fruit flies to ferry the gene editor Cas9 into muscle cells.

By Brianna Abbott
5 August 2026 | 5 min read

Textbook model of hippocampus’s role in memory may need updating

The CA3 region, long thought to have just one circuit, has two, sporting different wiring and functions, a new preprint suggests.

By Alissa de Chassey
4 August 2026 | 5 min read