Arbaclofen
Recent articles
Going on Trial: Gene therapy for Rett; return to arbaclofen
This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.
Going on Trial: Gene therapy for Rett; return to arbaclofen
This month’s newsletter looks at the early safety data from the first gene therapy trial for Rett syndrome, among other drug development news.
Multi-lab study hints at benefits of long-tested autism drug
The results lend support for clinical trials of arbaclofen in people with an autism-linked condition, the researchers say.
Multi-lab study hints at benefits of long-tested autism drug
The results lend support for clinical trials of arbaclofen in people with an autism-linked condition, the researchers say.
Swings and misses with Jeremy Veenstra-VanderWeele
A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.
Swings and misses with Jeremy Veenstra-VanderWeele
A careful clinician who prizes evidence, Jeremy Veenstra-VanderWeele is happy to embrace trial failures, as long as he learns from them.
Null and Noteworthy: Arbaclofen results; another oxytocin edition
New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.
Null and Noteworthy: Arbaclofen results; another oxytocin edition
New data from clinical trials of arbaclofen and oxytocin underscore the murkiness of null results. Plus, researchers seek clarity on the neurodevelopmental effects of oxytocin during childbirth.
Trials of arbaclofen for autism yield mixed results
Autistic children taking the drug showed improvements in some behaviors but not in their social skills.
Trials of arbaclofen for autism yield mixed results
Autistic children taking the drug showed improvements in some behaviors but not in their social skills.
Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses
Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.
Going on Trial: Arbaclofen reboot; cell implants; psilocybin microdoses
Going on Trial rounds up new developments in autism-related drug trials. This month we’re revisiting decade-old data from a trial of arbaclofen for fragile X syndrome and looking into a new implant-based approach to quelling seizures, among other treatment strategies.
Visual task flags autistic people who respond to GABA agonists
The investigational drug arbaclofen makes autistic people's brains respond to a visual task more like non-autistic people's brains do.
Visual task flags autistic people who respond to GABA agonists
The investigational drug arbaclofen makes autistic people's brains respond to a visual task more like non-autistic people's brains do.
Autism-related conditions linked to altered visual perception
A test of binocular rivalry may distinguish between autism subtypes and help researchers screen the efficacy of certain drugs.
Autism-related conditions linked to altered visual perception
A test of binocular rivalry may distinguish between autism subtypes and help researchers screen the efficacy of certain drugs.
Brain’s prefrontal cortex conducts symphony of social players
A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.
Brain’s prefrontal cortex conducts symphony of social players
A brain region that orchestrates responses to social cues and aids decision-making may be off tempo in autism.
Study calls into question chemical messenger’s role in autism
New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.
Study calls into question chemical messenger’s role in autism
New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.
Explore more from The Transmitter
Machine learning spots neural progenitors in adult human brains
But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.
Machine learning spots neural progenitors in adult human brains
But the finding has not settled the long-standing debate over the existence and extent of neurogenesis during adulthood, says Yale University neuroscientist Juan Arellano.
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
Xiao-Jing Wang outlines the future of theoretical neuroscience
Wang discusses why he decided the time was right for a new theoretical neuroscience textbook and how bifurcation is a key missing concept in neuroscience explanations.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.
Memory study sparks debate over statistical methods
Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.