Animal models

Recent articles

Different colored rectangles form the shapes of a bird, fish and insect.

Systems and circuit neuroscience need an evolutionary perspective

To identify fundamental neuroscientific principles that generalize across species, neuroscientists must frame their research through an evolutionary lens.

By Karl Farrow, Katja Reinhard
16 July 2025 | 7 min listen
Researcher holds a mouse perched on a glass cylinder.

NIH proposal sows concerns over future of animal research, unnecessary costs

The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.

By Claudia López Lloreda
15 July 2025 | 6 min listen
A fly over a background of waves of different colors.

Drosophila, like vertebrates, filter sensory information during sleep

Predictive sensory processing in sleeping Drosophila echoes vertebrate research, establishing an evolutionarily conserved neural signature of sleep.

By Siddhant Pusdekar
8 July 2025 | 5 min listen
Research image of excitatory neurons in the mouse hippocampus.

Spatial learning circuitry fluctuates in step with estrous cycle in mice

Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

By Sydney Wyatt
25 June 2025 | 6 min listen
Photograph of a moth.

Star-responsive neurons steer moths’ long-distance migration

Cells in the bogong moth brain respond to astral landmarks to orient the insects in the direction they need to go.

By Angie Voyles Askham
18 June 2025 | 5 min listen
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 5 min listen

Escaping groupthink: What animals’ behavioral quirks reveal about the brain

Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

By Angie Voyles Askham
23 May 2025 | 10 min listen
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read
Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read
Research image of human cortical neurons xenotransplanted into a mouse brain for months.

In vivo veritas: Xenotransplantation can help us study the development and function of human neurons in a living brain

Transplanted cells offer insight into human-specific properties, such as a lengthy cortical development and sensitivity to neurodevelopmental and neurodegenerative disease.

By Pierre Vanderhaeghen
7 April 2025 | 9 min listen

Explore more from The Transmitter

US dollar bills arranged in a circle.

Quantifying funding sources across neuroscience labs

We want to hear from you about the sources of funding for your research.

By Claudia López Lloreda
18 July 2025 | 1 min read
A disembodied arm holds a megaphone.

What kinds of support do early-career researchers need?

Help The Transmitter and Neuromatch bolster the next generation of neuroscientists.

By The Transmitter, Neuromatch
18 July 2025 | 1 min read
Research image of duplicated data in a now-retracted paper.

Alzheimer’s scientist forced to retract paper during his own replication effort

Gary Dunbar, a neuroscientist at Central Michigan University, was attempting to redo the 2020 paper after a collaborator admitted to using flawed data in the original work.

By Brendan Borrell
18 July 2025 | 4 min read