Alzheimer’s disease

Recent articles

Burke Neurological Institute.

Exclusive: Brain and spinal cord institute halts research, citing funding problems

The Burke Neurological Institute, which calls itself “the only research institute in the U.S. dedicated to finding treatments to repair the brain and spinal cord,” ceased research operations on 22 May.

By Lauren Schenkman
4 June 2026 | 5 min read
Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
Research image of stem cells derived from people of African ancestry.

Bringing African ancestry into cellular neuroscience

Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.

By Lauren Schenkman
14 January 2026 | 7 min read
Two goats headbutting.

How goats can model neurodegeneration

Since debunking an urban legend that headbutting animals don’t damage their brain, Nicole Ackermans has been investigating how the behavior correlates with neurodegeneration.

By Calli McMurray
7 January 2026 | 6 min read
Portion of The Transmitter’s state of neuroscience semantic map.

Putting 50 years of neuroscience on the map

Navigate the rise and fall of research topics over five decades using our interactive map, which is based on a semantic analysis of nearly 350,000 abstracts in leading neuroscience journals.

By The Transmitter
15 November 2025 | 3 min read
Research image of duplicated data in a now-retracted paper.

Alzheimer’s scientist forced to retract paper during his own replication effort

Gary Dunbar, a neuroscientist at Central Michigan University, was attempting to redo the 2020 paper after a collaborator admitted to using flawed data in the original work.

By Brendan Borrell
18 July 2025 | 4 min read
Illustration of complex, intersecting biological structures.

Everything, everywhere, all at once: Inside the chaos of Alzheimer’s disease

To truly understand Alzheimer’s disease, we may need to take a systems approach, in which inflammation, vascular injury, impaired glucose metabolism and other factors interact in complex ways.

By Michael A. Yassa
16 June 2025 | 7 min read
Abstract illustration of a human brain.

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt

In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”

By Nicole Rust
10 June 2025 | 9 min read
Research image of cell types in the human brain.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology

Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

By Ed Lein, Hongkui Zeng
24 March 2025 | 7 min read

Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down

5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.

By Shaena Montanari
4 February 2025 | 0 min watch

Explore more from The Transmitter

Research image of cell-surface protein LPHN2.

‘Push-pull’ recipe for neural wiring used in multiple brain regions

A versatile pair of proteins steers neurons toward their targets and helps establish the brain’s sensory maps, new studies suggest.

By Holly Barker
5 June 2026 | 5 min read
Research image showing dopamine level spikes.

Reward-learning algorithm hardwired into dopamine circuit

The finding bolsters the canonical model of reward prediction error, which has come under scrutiny in recent years.

By Natalia Mesa
5 June 2026 | 5 min read
Photo collage of Tempest McDonald.

When autistic kids grow up, Chapter 1: Those people

What leads an autism researcher to publish an intentionally inflammatory paper accusing the NIH of discrimination?

By Brady Huggett
4 June 2026 | 24 min listen