This paper changed my life

Recent articles

Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.

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This paper changed my Life: Bill Newsome reflects on a quadrilogy of classic visual perception studies

The 1970s papers from Goldberg and Wurtz made ambitious mechanistic studies of higher brain functions seem feasible.

By Bill Newsome
21 February 2025 | 6 min read
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This paper changed my life: ‘A massively parallel architecture for a self-organizing neural pattern recognition machine,’ by Carpenter and Grossberg

This paper taught me that we can use mathematical modeling to understand how neural networks are organized—and led me to a doctoral program in the department led by its authors.

By Luiz Pessoa
6 January 2025 | 3 min read
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This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab

This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.

By Anne E. West
27 November 2024 | 5 min read
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This paper changed my life: ‘Spontaneous cortical activity reveals hallmarks of an optimal internal model of the environment,’ from the Fiser Lab

Fiser’s work taught me how to think about grounding computational models in biologically plausible implementations.

By Megan Peters
16 October 2024 | 6 min listen
Illustration of a brain.

This paper changed my life: ‘Response of hippocampal synapses to natural stimulation patterns,’ by Dobrunz and Stevens

The work demonstrated how to effectively combine controlled in-vitro experiments and the messiness of natural brain patterns.

By Robert Froemke
17 September 2024 | 4 min read
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This paper changed my life: ‘Selective erasure of a fear memory’ from the Josselyn Lab

This groundbreaking 2009 paper set a foundation for the types of memories researchers could manipulate and inspired my own approach to science.

By Steve Ramirez
6 August 2024 | 5 min read

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Cara Pugliese.

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The termination is one of more than 1,000 employee cuts at the U.S. agency this week.

By Rachel Zamzow
21 February 2025 | 3 min read
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Science must step away from nationally managed infrastructure

Scientific data and independence are at risk. We need to work with community-driven services and university libraries to create new multi-country organizations that are resilient to political interference.

By Dan Goodman
20 February 2025 | 7 min read
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Familiar autism-linked genes emerge from first analysis of Latin American cohort

The findings, detailed in a January preprint, suggest autism’s fundamental biology is the same regardless of ancestry. But questions remain.

By Laura Dattaro
20 February 2025 | 5 min read