Systems neuroscience

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Research image of a mouse hippocampus.

Hippocampus builds reputation as ‘general-purpose statistical learning machine’

New cross-species findings may help settle a long-standing debate about whether the hippocampus is required for passive learning.

By Natalia Mesa
10 March 2026 | 5 min read
Figure in profile walking through the woods holding a branch that resembles a dendrite.

Dendrites help neuroscientists see the forest for the trees

Dendritic arbors provide just the right scale to study how individual neurons reciprocally interact with their broader circuitry—and are our best bet to bridge cellular and systems neuroscience.

By Justin O’Hare
27 February 2026 | 7 min read
Gloved hand reaches out to touch a mouse.

This paper changed my life: Ishmail Abdus-Saboor on balancing the study of pain and pleasure

A 2013 Nature paper from David Anderson’s lab revealed a group of sensory neurons involved in pleasurable touch and led Abdus-Saboor down a new research path.

By Ishmail Abdus-Saboor
13 February 2026 | 7 min read
A network of connected dots of light hovers inside a translucent human head, with figures in lab coats pointing to it from the foreground.

Computational psychiatry needs systems neuroscience

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research.

By Michael Halassa
13 January 2026 | 7 min read
Mouse on top of drinking water spout in crowded cage.

Cracking the neural code for emotional states

Rather than act as a simple switchboard for innate behaviors, the hypothalamus encodes an animal's internal state, which influences behavior.

By Natalia Mesa
8 January 2026 | 8 min read

Explore more from The Transmitter

Tom Griffiths describes how neural networks, logic and probability theory together explain cognition

In his new book, “The Laws of Thought,” Griffiths shows how these three pillars of study complement one another and together form a solid foundation to eventually explain all of our cognition, from brain to mind.

By Paul Middlebrooks
11 March 2026 | 100 min listen
illustration of cell layers

This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments

In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.

By Talia Lerner
11 March 2026 | 6 min read
Research figure depicting variation across the alpha subunit of the Nav1.2 sodium channel.

Portfolio of SCN2A gene variants, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 9 March.

By Jill Adams
10 March 2026 | 2 min read

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