Systems neuroscience

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Researcher hands and mice navigate a series of connected spaces and paths.

To understand decision-making, we need to truly challenge lab animals

Complex, multidimensional tasks that unfold over time could reveal how different brain areas work together to support decisions.

By Chand Chandrasekaran
20 April 2026 | 6 min read
A fragmenting cube hovers over a person reading a book.

Error equation predicts brain’s ability to generalize

Four statistical measurements of neural network geometry capture how well brains and artificial networks use what they already know to solve new problems, a study suggests.

By Natalia Mesa
10 April 2026 | 5 min read
Digital model of a fly next to a digital model of a nematode.

‘Digital sphinx’ raises questions about connectome models

The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

By Natalia Mesa
2 April 2026 | 5 min read

Head direction cells stably orient mice to outside world

The cells’ representations show little drift over time—unlike those of other navigation system neurons—and may provide a “rigid backbone” for more flexible sensory and cognitive responses.

By Angie Voyles Askham
25 March 2026 | 0 min watch
Research image of a mouse hippocampus.

Hippocampus builds reputation as ‘general-purpose statistical learning machine’

New cross-species findings may help settle a long-standing debate about whether the hippocampus is required for passive learning.

By Natalia Mesa
10 March 2026 | 5 min read

Explore more from The Transmitter

The silent majority: How astrocytes shape the brain across scales

Melissa Cooper talks to Mac Shine about her new work that reveals how these glial cells—long dismissed as the brain’s housekeepers—wire together in precise, long-range networks that remodel in response to experience.

By Mac Shine
12 May 2026 | 29 min watch
Research image showing brain activity related to sensory sensitivity and hypoconnectivity

Untangling genetic effects, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 11 May.

By Jill Adams
12 May 2026 | 2 min read
Illustration of stacks of papers.

The next unit of science: Is the scientific paper due to be replaced?

Artificial intelligence is pushing scientific publishing to the brink. For a field as sprawling as neuroscience, the crisis may also be an opportunity to finally connect findings across subfields.

By Tim Requarth
11 May 2026 | 11 min read