SYNGAP1 2020

Recent articles

SYNGAP1 protein between neurons.
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Reactions from the 2020 SYNGAP1 Scientific Conference

Spectrum is covering the 2020 International SYNGAP1 Scientific Conference, which took place virtually because of the coronavirus pandemic. Here we’re highlighting researchers’ reactions to noteworthy presentations.

By Peter Hess
25 November 2020 | 6 min read
Young zebrafish have transparent skin, which allows researchers to track the movements of glowing beads of excrement through their gut.

Zebrafish and ‘Smurf cakes’ link autism gene mutation to digestive woes

Mutations in a top autism gene called SYNGAP1 slow the rate at which zebrafish digest food and pass waste, and may also disrupt gut function in people.

By Peter Hess
24 November 2020 | 5 min read

Mice reveal roots of sensory issues tied to top autism gene

Mice with mutations in the autism-linked gene SYNGAP1 have trouble sensing touch, which may stem in part from brain-circuit alterations and dulled alertness.

By Peter Hess
23 November 2020 | 4 min read

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Cell population in brainstem coordinates cough, new study shows

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Capitol building
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In updated U.S. autism bill, Congress calls for funding boost, expanded scope

The current Autism CARES Act sunsets in late September.

By Rachel Zamzow
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Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read