Synaptic vesicles

Recent articles

Illustrated portrait of Tim Ryan.

Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission

Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”

By Brady Huggett
1 October 2024 | 70 min listen
lllustration of the junction between two nerve cells.

Multi-omics study captures CNTNAP2’s far-ranging effects

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

By Charles Q. Choi
8 December 2022 | 4 min read
Oil and water with colors behind: blue, green, yellow and red.

How microscopic ‘condensates’ in cells might contribute to autism

A controversial idea about how cells compartmentalize their contents into droplets — like beads of oil in water — could be key to understanding autism, says Julie Forman-Kay.

By Angie Voyles Askham
23 February 2021 | 7 min read

New method exposes structures inside ‘rainbow’ of brain cells

Molecules from alpacas may enable scientists to identify cell types in the brain while also revealing their interior structures.

By Chloe Williams
4 January 2019 | 0 min watch

Dividing autism; novel messengers; million-dollar mark and more

A researcher proposes splitting autism into subtypes, mitochondria make neurotransmitters, and highly successful grantees may face a funding cap.

By Emily Willingham
11 May 2018 | 3 min read

New tool spotlights neuron junctions in living human brains

A new imaging technique allows researchers to illuminate the junctions between neurons in a living person’s brain.

By Rachel Zamzow
19 August 2016 | 2 min read
Spectrum from The Transmitter.

Rainbow of dyes maps neurons’ tangled paths in brain

A new method that lets researchers trace the paths of many neurons at once may reveal how neurons go astray in autism.

By Kate Yandell
13 May 2015 | 3 min read
Spectrum from The Transmitter.

Suite of methods yields complex model of neuronal junctions

Researchers debuted a three-dimensional model of an average synapse, the point of connection between neurons, in the 30 May issue of Science.

By Kate Yandell
2 July 2014 | 2 min read
Spectrum from The Transmitter.

Molecular mechanisms: Autism gene establishes brain links

The autism-linked protein MET is expressed at the junctions between neurons during early brain development in mice, suggesting that it helps establish the connections, according to a study published 21 June in The Journal of Comparative Neurology.

By Jessica Wright
27 August 2013 | 2 min read
Spectrum from The Transmitter.

Researchers watch as proteins travel to neuronal junctions

Using high-resolution microscopy, researchers can watch as signaling complexes assemble at neuronal junctions in zebrafish embryos, according to a study published 17 April in Cell Reports.

By Jessica Wright
8 May 2013 | 2 min read

Explore more from The Transmitter

Close-up of high-resolution fMRI images.

Functional MRI can do more than you think

Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.

By Laura Lewis
14 April 2025 | 6 min read
People help each other climb up a supersized human brain.

As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap

Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.

By Christian Cazares, Maribel Patiño
11 April 2025 | 5 min read
Research image of two mouse brain slices.

Split gene therapy delivers promise in mice modeling Dravet syndrome

The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.

By Holly Barker
10 April 2025 | 5 min read