Synaptic

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This podcast focuses on the people, the science and the challenges in neuroscience.

The logo of the Synaptic podcast.

Season 2 of ‘Synaptic’ draws to a close

Season 3 will begin next year.

By Brady Huggett
1 November 2024 | 2 min listen
Illustrated portrait of Tim Ryan.

Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission

Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”

By Brady Huggett
1 October 2024 | 70 min listen
Illustrated portrait of Lin Tian.

Biosensors and being fearless with Lin Tian

Tian discusses protein function and structure, and the historic city in China where she was born.

By Brady Huggett
1 September 2024 | 62 min listen
Illustrated portrait of Catherine Dulac.

Male and female brains, Proust, and Catherine Dulac

The 2021 Breakthrough Prize winner explains how reading widely shaped her worldview, and discusses the vomeronasal organ.

By Brady Huggett
1 August 2024 | 81 min listen
Illustrated portrait of So Hyun “Sophy” Kim.

Diagnosing autism and teaching neurodiversity with So Hyun “Sophy” Kim

The Korea University professor on her path to autism research and studying in the United States.

By Brady Huggett
1 July 2024 | 67 min listen
Illustrated portrait of Eve Marder

Eve Marder, neural circuits and being heard

The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.

By Brady Huggett
1 June 2024 | 79 min listen
Illustrated portrait of Emily Finn.

Brain connectivity and letting the data speak with Emily Finn

The Dartmouth College researcher talks about her quest to understand behavior and doing neuroscience “in the woods.”

By Brady Huggett
1 May 2024 | 70 min listen
Illustrated portrait of Loren Frank.

The value of math and spatial learning with Loren Frank

The Howard Hughes Medical Institute investigator discusses what drew him to study the brain and his current work at the University of California, San Francisco.

By Brady Huggett
1 April 2024 | 62 min listen
Illustrated portrait of Lauren O’Connell.

Setting up a frog colony and pair bonding with Lauren O’Connell

To become a scientist, O’Connell first needed to leave the family farm.

By Brady Huggett
1 March 2024 | 63 min listen
Illustrated portrait of André Fenton.

Being uncomfortable and PKMzeta with André Fenton

The director of the Center for Neural Science shares a ghost story and talks about his collaboration with Todd Sacktor.

By Brady Huggett
1 February 2024 | 81 min listen

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Grid of human brain scans.

Dose, scan, repeat: Tracking the neurological effects of oral contraceptives

We know little about how the brain responds to oral contraceptives, despite their widespread use. I am committed to changing that: I scanned my brain 75 times over the course of a year and plan to make my data openly available.

By Carina Heller
20 January 2025 | 7 min read
Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
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Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read