Statistics

Recent articles

Research images shows areas of cortex that differed across scans of variable quality.

Poor image quality introduces systematic bias into large neuroimaging datasets

Analyses that include low-quality MRI data underestimate cortical thickness and overestimate cortical surface area, according to new findings from the Adolescent Brain Cognitive Development (ABCD) Study.

By Natalia Mesa
31 July 2025 | 5 min read
Overlapping speech bubbles.

Memory study sparks debate over statistical methods

Critics of a 2024 Nature paper suggest the authors failed to address the risk of false-positive findings. The authors argue more rigorous methods can result in missed leads.

By Katie Moisse
2 July 2025 | 5 min read
An opaque cube is repeated multiple times to create the appearance of overlapping cubes.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read
A curly line connects two pencils that are hovering over overlapping speech bubbles.

Say what? The Transmitter’s top quotes of 2024

“We’ve cured mouse-heimer’s thousands of times...”—find out who said this to a Transmitter reporter, and read our other favorite quotes from the past year.

By The Transmitter
23 December 2024 | 2 min read
Illustration of a single digitally rendered figure wandering a fragmented and distorted virtual environment.

Nonsense correlations and how to avoid them

This statistical error is common in systems neuroscience. Fortunately, straightforward methods can help you prevent it.

By Kenneth Harris
12 August 2024 | 6 min read

Explore more from The Transmitter

Genetic profiles separate early, late autism diagnoses

Age at diagnosis reflects underlying differences in common genetic variants and developmental trajectories among people with autism.

By Natalia Mesa
27 November 2025 | 5 min read

To persist, memories surf molecular waves from thalamus to cortex

During the later stages of learning, the mouse brain progressively activates transcriptional regulators that drive memory consolidation.

By Claudia López Lloreda
26 November 2025 | 4 min read

Sex hormone boosts female rats’ sensitivity to unexpected rewards

During the high-estradiol stages of their estrus cycle, female rats learn faster than they do during other stages—and than male rats overall—thanks to a boost in their dopaminergic response to reward, a new study suggests.

By Angie Voyles Askham
26 November 2025 | 5 min read

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