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X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Some who lack autism diagnosis carry variants tied to the condition
The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.
Loss of autism-linked gene dampens social interactions in animals
Mice and zebrafish missing the GIGYF1 gene show social traits reminiscent of autism, though the molecular underpinnings are unclear.
Loss of autism-linked gene dampens social interactions in animals
Mice and zebrafish missing the GIGYF1 gene show social traits reminiscent of autism, though the molecular underpinnings are unclear.
Simons Foundation clinical research head Wendy Chung to lead Boston Children’s pediatrics department
Chung, a clinical and molecular geneticist, plans to continue serving as principal investigator of two large research projects involving cohorts of people with autism and related neurodevelopmental conditions.
Simons Foundation clinical research head Wendy Chung to lead Boston Children’s pediatrics department
Chung, a clinical and molecular geneticist, plans to continue serving as principal investigator of two large research projects involving cohorts of people with autism and related neurodevelopmental conditions.
New tool aims to capture full breadth of repetitive behaviors
The measure breaks the behaviors down into eight distinct subdomains — categorization that could prove useful for clinical trials, its creator says.
New tool aims to capture full breadth of repetitive behaviors
The measure breaks the behaviors down into eight distinct subdomains — categorization that could prove useful for clinical trials, its creator says.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
X-chromosome variants help explain autism’s sex bias
The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.
Autism diagnosis in adulthood tied to increased burden of psychiatric conditions
Mood, anxiety, personality and eating disorders more commonly affect autistic people diagnosed in adulthood than those diagnosed in childhood.
Autism diagnosis in adulthood tied to increased burden of psychiatric conditions
Mood, anxiety, personality and eating disorders more commonly affect autistic people diagnosed in adulthood than those diagnosed in childhood.
Explore more from The Transmitter
Digitization of ‘breathtaking’ neuroanatomy slide collection offers untapped research gold mine
Thousands of histological sections of vertebrate brains—including from spiny dogfish, turtles and more—are newly available online.
Digitization of ‘breathtaking’ neuroanatomy slide collection offers untapped research gold mine
Thousands of histological sections of vertebrate brains—including from spiny dogfish, turtles and more—are newly available online.
Personalized medicine; astroglia organoids; fast track for fragile X drug
Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.
Personalized medicine; astroglia organoids; fast track for fragile X drug
Here is a roundup of autism-related news and research spotted around the web for the week of 20 January.
Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.
Neuroscientists need to do better at explaining basic mental health research
The knowledge gap between scientists, health-care professionals, policymakers and people with mental health conditions is growing, slowing the translation of basic science to new treatments. Like lawyers learning to present a case to the court, scientists should learn to educate nonscientists about their findings.