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Recent articles

Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read
Illustration of hands sewing red and white threads in a DNA-like pattern into a blue-gray fabric.

Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes

People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.

By Holly Barker
3 October 2024 | 5 min read

Genome structure could be key factor in some forms of autism

Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.

By Giorgia Guglielmi
28 March 2024 | 4 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
Blurry photograph of a crowd of people on a street.

Some who lack autism diagnosis carry variants tied to the condition

The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.

By Charles Q. Choi
13 July 2023 | 4 min read
Research heatmap showing mice associating more with familiar mice than unfamiliar ones.

Loss of autism-linked gene dampens social interactions in animals

Mice and zebrafish missing the GIGYF1 gene show social traits reminiscent of autism, though the molecular underpinnings are unclear.

By Holly Barker
28 April 2023 | 4 min read
Headshot of Wendy Chung.

Simons Foundation clinical research head Wendy Chung to lead Boston Children’s pediatrics department

Chung, a clinical and molecular geneticist, plans to continue serving as principal investigator of two large research projects involving cohorts of people with autism and related neurodevelopmental conditions.

By Jef Akst
14 February 2023 | 5 min read
A woman sits and works at a laptop while her daughter sits next to her and looks out of a glass door.

New tool aims to capture full breadth of repetitive behaviors

The measure breaks the behaviors down into eight distinct subdomains — categorization that could prove useful for clinical trials, its creator says.

By Laura Dattaro
13 January 2023 | 5 min read
Illustration of an X chromosome against a black background.

X-chromosome variants help explain autism’s sex bias

The rare variants are also linked to ADHD and Tourette syndrome, two other conditions that disproportionately affect boys and men.

By Charles Q. Choi
24 October 2022 | 4 min read
A patient sits in the waiting room of a doctor's office.

Autism diagnosis in adulthood tied to increased burden of psychiatric conditions

Mood, anxiety, personality and eating disorders more commonly affect autistic people diagnosed in adulthood than those diagnosed in childhood.

By Charles Q. Choi
19 September 2022 | 4 min read

Explore more from The Transmitter

Expediting clinical trials for profound autism: Q&A with Matthew State

Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.

By Lauren Schenkman
24 April 2025 | 8 min read
Illustration of astrocytes in a petri dish.

This paper changed my life: Shane Liddelow on two papers that upended astrocyte research

A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.

By Shane Liddelow
23 April 2025 | 6 min read

Dean Buonomano explores the concept of time in neuroscience and physics

He outlines why he thinks integrated information theory is unscientific and discusses how timing is a fundamental computation in brains.

By Paul Middlebrooks
23 April 2025 | 111 min listen