SFN 2015

Recent articles

Neuron tag may shield synapses from brain’s pruning shears

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

By Nicholette Zeliadt
12 November 2018 | 4 min read

Three autism mouse models marked by defects in same circuit

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

By Nicholette Zeliadt
8 November 2017 | 4 min read

Network analysis gives clues to other ailments in autism

Genes linked to autism are associated with a variety of other ailments, including cancer, heart conditions, autoimmune disorders and gut problems.

By Nicholette Zeliadt
25 October 2016 | 3 min read
Spectrum from The Transmitter.

Maternal immune molecule triggers autism symptoms in male mice

Rare antibodies taken from the blood of women who have a child with autism cause brain structure changes and autism-like symptoms in male mice.

By Nicholette Zeliadt
7 November 2015 | 4 min read
Spectrum from The Transmitter.

Over-synched brains trigger out-of-step social behavior

People with autism show excessively synchronized activity between brain regions while conversing with others.

By Sarah DeWeerdt
22 October 2015 | 4 min read
Spectrum from The Transmitter.

Male mice more vulnerable to tilt of gut-brain axis

Early disruption of the microbes that inhabit the gut can alter a mouse’s sociability long term.

By Sarah DeWeerdt
22 October 2015 | 4 min read
Spectrum from The Transmitter.

For autism mouse models, gender matters

The mutation that leads to Angelman syndrome may affect the brains of female mice more severely than those of male mice.

By Jessica Wright
22 October 2015 | 3 min read
Spectrum from The Transmitter.

Autism model reveals brain processes behind ‘super’ skills

Structural changes in the connections between neurons may underlie the enhanced learning and motor skills of a mouse model of autism.

By Nicholette Zeliadt
21 October 2015 | 4 min read
Spectrum from The Transmitter.

One form of immune gene tracks with autism traits

A variant in a gene that regulates immune responses is more common in children with autism than in those without this disorder.

By Katie Moisse
21 October 2015 | 2 min read
Spectrum from The Transmitter.

Prairie vole study digs up link between Prozac, oxytocin

Prairie vole pups exposed to the antidepressant fluoxetine in the womb show autism-like behaviors and lose some receptors for oxytocin and vasopressin.

By Rachel Zamzow
21 October 2015 | 3 min read

Explore more from The Transmitter

Colorful illustration of a latticework of proteins.

Cracking the code of the extracellular matrix

Despite evidence for a role in plasticity and other crucial functions, many neuroscientists still view these proteins as “brain goop.” The field needs technical advances and a shift in scientific thinking to move beyond this outdated perspective.

By Anna Victoria Molofsky
17 January 2025 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read
Research image highlighting different brain regions.

X marks the spot in search for autism variants

Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.

By Holly Barker
16 January 2025 | 6 min read