Schizophrenia

Recent articles

Novel assembloid illuminates serotonin changes linked to 22q11.2 deletion

The combination of a serotonin-producing organoid with an organoid based on the developing cerebral cortex offers a new way to investigate neuromodulation.

By Sarah DeWeerdt
30 April 2026 | 0 min watch
Data visualization from a genome-wide association study.

Revised statistical bar extracts less-common variants from autism genetics studies

Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.

By Holly Barker
12 March 2026 | 4 min read
A network of connected dots of light hovers inside a translucent human head, with figures in lab coats pointing to it from the foreground.

Computational psychiatry needs systems neuroscience

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research.

By Michael Halassa
13 January 2026 | 7 min read
Hands arrange various shapes over a color background.

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 29 min read
Illustration of a line graph emanating from a beaker.

Null and Noteworthy, relaunched: Probing a schizophrenia biomarker

This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.

By Laura Dattaro
28 February 2025 | 5 min read
Illustration of two silhouettes overlaid by opaque square panels.

Why hasn’t genetics taught us more about schizophrenia?

Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

By Joshua R. Sanes
18 February 2025 | 8 min read

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read

Explore more from The Transmitter

Two opposing arrows.

European Research Council backtracks on stricter grant resubmission rules

The swift reversal came after more than 1,000 scientists signed an open letter protesting the rules last week.

By Lauren Schenkman
1 May 2026 | 4 min read
leech illustration.

What leeches reveal about movement

After encountering setbacks in her study of the neuromuscular system in vertebrates, Lidia Szczupak turned to leeches to explore how the nervous system coordinates movement.

By Claudia López Lloreda
1 May 2026 | 5 min read
Conference attendees.

Reporter’s notebook: Highlights from INSAR 2026

At the 25th annual meeting of the International Society for Autism Research, scientists, clinicians and self-advocates gathered to discuss topics such as autism genetics and the gap between clinical trials and real-world benefits.

By Diana Kwon
30 April 2026 | 6 min read