Schizophrenia

Recent articles

Stock illustration of strands of DNA with mutations.

Number of autism-linked genes more than triples in new analyses

In addition to a new preprint that expands the list of genes tied to the condition, two related analyses reveal how variants in those genes contribute to genetic susceptibility.

By Holly Barker
8 October 2026 | 6 min read
Structural MRI scans of people with Alzheimer’s disease and depression.

Neuropsychiatric MRI brain signatures fail reproducibility test

Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.

By Holly Barker
12 August 2026 | 5 min read

Novel assembloid illuminates serotonin changes linked to 22q11.2 deletion

The combination of a serotonin-producing organoid with an organoid based on the developing cerebral cortex offers a new way to investigate neuromodulation.

By Sarah DeWeerdt
30 April 2026 | 0 min watch
Data visualization from a genome-wide association study.

Revised statistical bar extracts less-common variants from autism genetics studies

Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.

By Holly Barker
12 March 2026 | 4 min read
A network of connected dots of light hovers inside a translucent human head, with figures in lab coats pointing to it from the foreground.

Computational psychiatry needs systems neuroscience

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research.

By Michael Halassa
13 January 2026 | 7 min read
Hands arrange various shapes over a color background.

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 29 min read
Illustration of a line graph emanating from a beaker.

Null and Noteworthy, relaunched: Probing a schizophrenia biomarker

This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.

By Laura Dattaro
28 February 2025 | 5 min read
Illustration of two silhouettes overlaid by opaque square panels.

Why hasn’t genetics taught us more about schizophrenia?

Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

By Joshua R. Sanes
18 February 2025 | 8 min read

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read

Explore more from The Transmitter

Barbara Finlay looking at a glass jar with a brain.

Remembering Barbara Finlay, ‘maverick’ of evolutionary neuroscience

Finlay, who died on 12 September, championed the idea that developmental constraints dictate how evolution sculpts brains, a concept she used to model the timing of hundreds of events and align them across mammalian species.

By Calli McMurray
23 October 2026 | 8 min read
A crow looking at a screen showing a circle of white dots on a black background.

Crows have brains ‘in the fast lane’

The birds accurately complete decision-making tasks twice as fast as primates, although their endbrains look considerably different.

By Sarah Thau
22 October 2026 | 4 min read
A boy manipulates blocks at a table while sitting across from a woman taking notes.

Prevalence of profound autism declines with new definition

The updated, more precise definition used in a CDC study includes adaptive scores.

By Brianna Abbott
22 October 2026 | 5 min read