Plasticity
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2025 Brain Prize honors pair of cancer neuroscientists
Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.
2025 Brain Prize honors pair of cancer neuroscientists
Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
Remembering Eleanor Maguire, ‘trailblazer’ of human memory
Maguire, mastermind of the famous London taxi-driver study, broadened the field and championed the importance of spatial representations in memory.
To beat the heat, hypothalamus neurons in mice ramp up their firing
The uptick may help the rodents acclimate to temperature hikes and keep their cool.
To beat the heat, hypothalamus neurons in mice ramp up their firing
The uptick may help the rodents acclimate to temperature hikes and keep their cool.
This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.
This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)
Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?
How to teach this paper: ‘Behavioral time scale synaptic plasticity underlies CA1 place fields,’ by Bittner and Milstein et al. (2017)
Katie Bittner, Aaron Milstein and their colleagues found that cellular learning can happen over longer timescales than Hebb’s rule predicts. How long should we wait to teach students about this phenomenon?
Eve Marder, neural circuits and being heard
The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.
Eve Marder, neural circuits and being heard
The National Medal of Science winner explains why she built her career around the crustacean and what it was like attending high school in a Hudson River town.
The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.
The question of regeneration—an excerpt from ‘Periphery: How Your Nervous System Predicts and Protects Against Disease’
In his recent book, Moses Chao makes the case that the peripheral nervous system can warn of future illnesses.
Neurons making memories shush their neighbors
When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.
Neurons making memories shush their neighbors
When neurons strengthen their synapses, they “infect” surrounding cells with a virus-like protein to weaken those cells’ excitatory connections, according to a new preprint.
Going deep: The Transmitter’s top long-form stories in 2023
Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.
Going deep: The Transmitter’s top long-form stories in 2023
Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.
Explore more from The Transmitter
Functional MRI can do more than you think
Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.
Functional MRI can do more than you think
Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.
As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap
Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.
As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap
Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.
Split gene therapy delivers promise in mice modeling Dravet syndrome
The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.