PDD-NOS

Recent articles

Illustration shows a boy with converging patterns overlapping; these lines signify autism and intellectual disability.

The blurred line between autism and intellectual disability

Doctors often conflate autism and intellectual disability, and no wonder: The biological distinction between them is murky. Scientific progress depends on knowing where the conditions intersect — and part ways.

By Emily Sohn
15 April 2020 | 15 min read
Photo: Autistic woman Becky Audette lies on a couch under a purple blanket.

Rebooting Becky’s brain

An electrical brain implant all but erased the obsessions that had consumed Becky Audette, years after her autism diagnosis. Could similar implants help other people with severe autism?

By Ingrid Wickelgren
12 September 2018 | 28 min read

Few people mourn Asperger syndrome’s loss from diagnostic manuals

Our concept of autism has evolved over the past 20 years, rendering redundant the diagnostic labels of Asperger syndrome and pervasive developmental disorder-not otherwise specified.

By David Skuse
9 May 2018 | 4 min read
People standing with shapes around them

The evolution of ‘autism’ as a diagnosis, explained

From a form of childhood schizophrenia to a spectrum of conditions, the characterization of autism in diagnostic manuals has a complicated history.

By Lina Zeldovich
9 May 2018 | 7 min read

Narrowing of ‘autism’ in DSM-5 runs counter to idea of broad spectrum

The strict definition of autism in the latest version of the diagnostic manual is antithetical to the idea that autism comes in a wide variety of forms.

By Brian Reichow, Fred Volkmar
9 May 2018 | 5 min read

Why the definition of autism needs to be refined

Five years after its latest revision, the manual used to diagnose autism is back under scrutiny, as evidence suggests it excludes some people on the spectrum.

By Lina Zeldovich
9 May 2018 | 14 min read

Why no one needs a diagnosis of ‘social communication disorder’

A diagnosis of social communication disorder only keeps people from a community and resources they desperately want and need.

By Helen Tager-Flusberg
17 April 2018 | 4 min read

Prevalence plateau; herbal inquiry; protein profile and more

Autism prevalence plateaued for the years 2014 to 2016, a review finds no evidence that herbal therapies for autism work, and a panel of four proteins in blood may distinguish children with autism.

By Emily Willingham
5 January 2018 | 4 min read
Spectrum from The Transmitter.

Wide awake: Why children with autism struggle with sleep

Half of children who have autism have trouble falling or staying asleep, which may make their symptoms worse. Scientists are just beginning to explore what goes wrong in the midnight hour.

By Ingfei Chen
7 October 2015 | 15 min read
Spectrum from The Transmitter.

Screening toddlers for autism is worthwhile

A Norwegian study published in February suggested that the Modified Checklist for Autism in Toddlers fails to detect many cases of autism at 18 months of age. The creators of the test explain why there’s more to the story.

By Deborah Fein, Diana Robins
29 April 2014 | 6 min read

Explore more from The Transmitter

Close-up of high-resolution fMRI images.

Functional MRI can do more than you think

Recent technological advances provide a range of new and different information about brain physiology. But taking full advantage of these gains depends on collaboration between engineers and neuroscientists.

By Laura Lewis
14 April 2025 | 6 min read
People help each other climb up a supersized human brain.

As federal funders desert mentorship programs for marginalized students, trainee-led initiatives fill the gap

Grassroots organizations, led by graduate students and postdoctoral researchers, are stepping up to provide neuroscience career training and guidance for students from marginalized backgrounds—and they need your support.

By Christian Cazares, Maribel Patiño
11 April 2025 | 5 min read
Research image of two mouse brain slices.

Split gene therapy delivers promise in mice modeling Dravet syndrome

The new approach overcomes viral packaging limitations by delivering SCN1A piecemeal and stitching it together in target cells.

By Holly Barker
10 April 2025 | 5 min read