Neurons

Recent articles

DNA strand.

Exon-skipping approach boosts levels of key Rett syndrome protein

Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.

By Giorgia Guglielmi
20 March 2026 | 5 min read
Research image of senescing cells.

Signs of aging vary across brain cells

Senescence presents differently depending on the cell type, toxic trigger and neighboring cells, two new studies find.

By Claudia López Lloreda
18 March 2026 | 4 min read
Research image of organoids derived from stem cell lines from people with intellectual disability, polymicroglia or microcephaly, alongside a control organoid.

New organoid atlas unveils four neurodevelopmental signatures

The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.

By Diana Kwon
17 December 2025 | 4 min read
A series of colored rectangles in a cosmos-like black space.

The challenge of defining a neural population

Our current approach is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics.

By Mark Humphries
11 August 2025 | 8 min read
Research image of a mouse brain with the same spot shown three times in different colors to show different neurochemical concentrations.

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 4 min read
An opaque cube is repeated multiple times to create the appearance of overlapping cubes.

Sounding the alarm on pseudoreplication: Q&A with Constantinos Eleftheriou and Peter Kind

Most studies of neurological disorders in mice erroneously treat multiple samples from a single animal as independent replicates, according to a new analysis. But scientists and journals can take steps to curb this practice.

By Lauren Schenkman
12 June 2025 | 6 min read
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 4 min read
Raphael Yuste leaning on a bench in his lab. A red filter colors the scene.

Releasing the Hydra with Rafael Yuste

Losing HHMI Investigator status prompted Yuste to study neural networks in a new way.

By Brady Huggett, Shaena Montanari
4 April 2025 | 10 min read
Research image of brain glucose levels in mice.

Food for thought: Neuronal fuel source more flexible than previously recognized

The cells primarily rely on glucose—rather than lactate from astrocytes—to generate energy, according to recent findings in mice.

By Giorgia Guglielmi
7 February 2025 | 6 min read

Explore more from The Transmitter

Research image of fibroblasts creating a seal that separates the blood vessels in the choroid plexus from the rest of the brain.

Newly identified barrier cells seal off choroid plexus from CSF, rest of brain

A long-overlooked layer of fibroblasts exists inside the choroid plexus of mice and humans, adding complexity to the area’s compartmentalization.

By Claudia López Lloreda
3 April 2026 | 4 min read
Digital model of a fly next to a digital model of a nematode.

‘Digital sphinx’ raises questions about connectome models

The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.

By Natalia Mesa
2 April 2026 | 5 min read
Astrocytes in a mouse brain.

Taking a closer look at astrocytes and autism

These glial cells are increasingly linked to neurodevelopmental conditions and the regulation of social behaviors and anxiety.

By The Transmitter
2 April 2026 | 2 min read