Neuromodulators

Recent articles

Archery target.

What should the field prioritize over the next 10 years?

Respondents pointed to a range of challenges in basic neuroscience—such as understanding naturalistic behaviors, intelligence and embodied cognition—and called for more circuit-level research, more precise brain recordings and more work in alternative models. Just as many pushed for a translational pivot.

By The Transmitter
15 November 2025 | 11 min read
Research image of serotonin and dopamine neurons manipulated simultaneously in mice.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning

Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

By Angie Voyles Askham
12 February 2025 | 5 min read

Explore more from The Transmitter

Connexiohuman Connexin 26 dodecamer at 90mmHg PCO2, pH7.4

Designer synapses edit brain circuits in living animals

The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.

By Simon Makin
23 June 2026 | 5 min read
Research image of cortical excitation–inhibition balance.

Role of GABA-A receptors in dup15q syndrome, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.

By Jill Adams
23 June 2026 | 2 min read
Thermal image of Danionella fish.

Exclusive: Janelia sunsets rodent work, launches transparent fish project

The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.

By Calli McMurray
22 June 2026 | 5 min read