Neuromodulators

Recent articles

Archery target.

What should the field prioritize over the next 10 years?

Respondents pointed to a range of challenges in basic neuroscience—such as understanding naturalistic behaviors, intelligence and embodied cognition—and called for more circuit-level research, more precise brain recordings and more work in alternative models. Just as many pushed for a translational pivot.

By The Transmitter
15 November 2025 | 11 min read
Research image of serotonin and dopamine neurons manipulated simultaneously in mice.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning

Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

By Angie Voyles Askham
12 February 2025 | 5 min read

Explore more from The Transmitter

Research image of locus coeruleus

Brain’s blue spot possesses unexpected structure-function ties

The spatial arrangement of neurons in the locus coeruleus of mice corresponds with the cells’ targets across the brain, according to a new study.

By Holly Barker
25 May 2026 | 4 min read
Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Hand points to letters on a board.

Still no proof for facilitated spelling methods

A systematic review into whether the “rapid prompting method” or “spelling to communicate” can help autistic people express themselves comes up empty yet again.

By Brendan Borrell
21 May 2026 | 6 min read