Neuromodulators

Recent articles

Archery target.

What should the field prioritize over the next 10 years?

Respondents pointed to a range of challenges in basic neuroscience—such as understanding naturalistic behaviors, intelligence and embodied cognition—and called for more circuit-level research, more precise brain recordings and more work in alternative models. Just as many pushed for a translational pivot.

By The Transmitter
15 November 2025 | 11 min read
Research image of serotonin and dopamine neurons manipulated simultaneously in mice.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning

Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

By Angie Voyles Askham
12 February 2025 | 5 min read

Explore more from The Transmitter

Brain registers spatial location outside hippocampus

A more complex picture of how an animal’s brain tracks its location is starting to emerge.

By Natalia Mesa
5 November 2026 | 1 min watch
Illustration of worm on top of a purple rock with neurons in the background.

The three-banded panther worm is rewriting the story of brain evolution

The animal has a brain structure all its own, according to a 2026 preprint. The finding hints that brains could have evolved centralization before regionalization.

By Sarah DeWeerdt
4 November 2026 | 7 min read

Does cognition happen in brain areas or between them?

Michael Cole explains how "brain flows" are the fundamental units of brain function and cognition.

By Paul Middlebrooks
4 November 2026 | 1 min read