Neuromodulators

Recent articles

Archery target.

What should the field prioritize over the next 10 years?

Respondents pointed to a range of challenges in basic neuroscience—such as understanding naturalistic behaviors, intelligence and embodied cognition—and called for more circuit-level research, more precise brain recordings and more work in alternative models. Just as many pushed for a translational pivot.

By The Transmitter
15 November 2025 | 11 min read
Research image of serotonin and dopamine neurons manipulated simultaneously in mice.

Dopamine ‘gas pedal’ and serotonin ‘brake’ team up to accelerate learning

Mice learn fastest and most reliably when they experience an increase in dopamine paired with an inhibition of serotonin in their nucleus accumbens, a new study shows, helping to resolve long-standing questions about the neuromodulators’ relationship.

By Angie Voyles Askham
12 February 2025 | 5 min read

Explore more from The Transmitter

Illustration of differing lines of data.

Eighteen teams analyzed the same neurophysiology dataset—and got wildly different answers

The “Brainhack” hackathon revealed that disagreement in neuroscience runs deeper than most researchers suspect—even in electrophysiology, a field that prides itself on hard data.

By Gaëlle Chapuis, Mattia Chini
1 June 2026 | 7 min read
Research image of inputs into a single neuron in the mouse visual cortex.

‘Unbelievably beautiful’ evidence extends Nobel Prize-winning model of vision

Orientation tuning—the ability to distinguish a horizontal line from a vertical one or something in between—originates in the visual cortex, according to new mouse synapse imaging experiments.

By Claudia López Lloreda
29 May 2026 | 5 min read
Illustration of people connecting basic science.

Bringing basic biology back to INSAR

As the International Society for Autism Research has grown over the past two decades, basic science has become less central, Christine Wu Nordahl says. This year, she and other meeting organizers aimed to change that.

By Diana Kwon
28 May 2026 | 6 min read