Neocortex

Recent articles

Research image of excitatory neurons in the mouse hippocampus.

Spatial learning circuitry fluctuates in step with estrous cycle in mice

Cyclic shifts in estradiol levels coincide with changes in dendritic spine density and the activity of place cells in the CA1 region of the hippocampus, a new study shows.

By Sydney Wyatt
25 June 2025 | 6 min listen

Rajesh Rao reflects on predictive brains, neural interfaces and the future of human intelligence

Twenty-five years ago, Rajesh Rao proposed a seminal theory of how brains could implement predictive coding for perception. His modern version zeroes in on actions.

By Paul Middlebrooks
18 December 2024 | 97 min listen
blood in a medical vial, closeup

Molecular signature may lead to blood test for autism

Researchers have identified a distinctive pattern of gene expression in the white blood cells of young autistic boys.

By Lauren Schenkman
31 October 2019 | 4 min read

Fathering geeks; GWAS weaknesses; Prozac protection and more

Paternal age drives ‘geek index’ scores, GWAS may have a big weakness, serotonin boosts mouse social behaviors, and what is science Tinder?

By Emily Willingham
23 June 2017 | 8 min read
Spectrum from The Transmitter.

Sequencing approach bares large variety of brain cell types

Analyzing gene expression in a vision center of the mouse brain has revealed 49 different classes of cells.

By Kate Yandell
24 February 2016 | 2 min read
Spectrum from The Transmitter.

Mathematical model of autism bridges brain, behavior

A mathematical model of the brain’s circuits shows how neurons stuck in overdrive could produce symptoms of autism. The model may reveal how autism-linked behaviors arise from underlying biology.

By Rachel Nuwer
13 August 2015 | 6 min read
Spectrum from The Transmitter.

Atlas charts gene activity in developing monkey brains

Researchers have for the first time mapped gene expression in the rhesus macaque brain from birth through adulthood. The atlas illuminates the expression patterns of genes likely to be important in autism.

By Kate Yandell
10 June 2015 | 3 min read
Spectrum from The Transmitter.

Spotted: Social cells; brain bulge

A cluster of neurons helps monkeys cooperate, and a human gene makes a mouse brain look like a person's.

By Katie Moisse
27 February 2015 | 3 min read
a chromosome unspools to become DNA

Autism gene guides early neuron development

The little-studied autism gene ANKRD11 helps to package DNA in the nucleus and plays a critical role in the early growth and positioning of neurons.

By Nicholette Zeliadt
12 February 2015 | 5 min read
Spectrum from The Transmitter.

New mouse model mimics brain abnormalities in autism

Mice with mutations in the autism-linked gene WDFY3 have enlarged brains reminiscent of those seen in some children with autism, according to a study published 8 September in Nature Communications.

By Nicholette Zeliadt
6 October 2014 | 5 min read

Explore more from The Transmitter

ABCD Study omits gender-identity data from latest release

The removal counteracts the goals of the longitudinal study by “pretending that some aspects of adolescent brain development don’t exist,” says sex differences researcher Nicola Grissom.

By Calli McMurray
11 July 2025 | 4 min read
Leafcutter ants carrying leaves.

Neuropeptides reprogram social roles in leafcutter ants

The mechanisms that control the labor roles of ants may also be conserved in naked mole rats, a new study shows.

By Shaena Montanari
11 July 2025 | 7 min listen
Illustration of overlapping, multi-colored human head silhouettes.

Perspectives from the field: Opinions in autism research

This collection of Spectrum articles from the past 12 months highlights expert perspectives on autism’s heritability and its link to biological sex, the value of transdiagnostic frameworks, and the field’s future, among other topics.

By Daisy Yuhas
10 July 2025 | 3 min read