Molecular neuroscience

Recent articles

Abstract illustration of a synaptic vesicle.

This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle

In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.

By Sandra Jurado
21 October 2025 | 6 min listen
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 7 min listen
Research image of a mouse brain with the same spot shown three times in different colors to show different neurochemical concentrations.

New dopamine sensor powers three-color imaging in live animals

The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.

By Diana Kwon
25 July 2025 | 5 min listen
Abstract illustration of a human brain.

‘Elusive Cures: Why Neuroscience Hasn’t Solved Brain Disorders—and How We Can Change That,’ an excerpt

In her new book, published today, neuroscientist Nicole Rust takes us on her personal quest to spell out the brain research community’s “Grand Plan.”

By Nicole Rust
10 June 2025 | 9 min read
Research image of developing axons in the fly brain.

How developing neurons simplify their search for a synaptic mate

Streamlining the problem from 3D to 1D eases the expedition—a strategy the study investigators deployed to rewire an olfactory circuit in flies.

By Calli McMurray
6 June 2025 | 7 min listen
Research image of a fiber optic implant in a mouse brain.

Bespoke photometry system captures variety of dopamine signals in mice

The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

By Sydney Wyatt
21 March 2025 | 5 min read
Four microphones on a table with speech bubbles above them.

The Transmitter’s favorite podcasts of 2024

Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

By The Transmitter
23 December 2024 | 1 min read

Hessameddin Akhlaghpour outlines how RNA may implement universal computation

Could the brain’s computational abilities extend beyond neural networks to molecular mechanisms? Akhlaghpour describes how natural universal computation may have evolved via RNA mechanisms.

By Paul Middlebrooks
26 November 2024 | 107 min listen
Illustration of overlapping silhouettes of two faces in profile facing a matrix of dots of various colors and sizes.

How to be a multidisciplinary neuroscientist

Neuroscience subfields are often siloed. Embracing an integrative approach during training can help change that.

By Austin Coley
15 November 2024 | 5 min read
Collage of different images of brains and mechanical devices in the background with a suitcase in the foreground.

What are mechanisms? Unpacking the term is key to progress in neuroscience

Mechanism is a common and powerful concept, invoked in grant calls and publication guidelines. But scientists use it in different ways, making it difficult to clarify standards in the field. We asked nine scientists to weigh in.

By Dani S. Bassett, Lauren N. Ross
7 October 2024 | 5 min read

Explore more from The Transmitter

Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry

The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.

By Calli McMurray
29 October 2025 | 7 min read
Headshots of Philip Adeniyi, Samir Ahboucha, Willias Masoch and Daniel Gams Massi.

First Pan-African neuroscience journal gets ready to launch

With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neuroscience research much-needed international visibility.

By Lauren Schenkman
28 October 2025 | 5 min listen
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

New method identifies two-hit genetic variation in autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 27 October.

By Jill Adams
28 October 2025 | 2 min read

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