Modeling

Recent articles

Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read

Gabriele Scheler reflects on the interplay between language, thought and AI

She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.

By Paul Middlebrooks
26 March 2025 | 96 min listen
Illustrated portrait of Kanaka Rajan.

How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan

The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.

By Olivia Gieger
9 October 2024 | 7 min read
Illustration of hands sewing red and white threads in a DNA-like pattern into a blue-gray fabric.

Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes

People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.

By Holly Barker
3 October 2024 | 5 min read
Illustration of cranes attempting to assemble a structure out of very small black squares.

Reconstructing dopamine’s link to reward

The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

By Angie Voyles Askham
13 September 2024 | 20 min listen
Illustration of cranes attempting to assemble a structure out of very small black squares.

Dopamine and the need for alternative theories

Some experimental findings are inconsistent with the dominant model of reward prediction error, highlighting the need for alternative testable and falsifiable models for dopamine function.

By Vijay Mohan K. Namboodiri
13 September 2024 | 7 min read
Illustration of several structures constructed out of small black squares, with scaffolding on some of the structures.

Does a new theory of dopamine replace the classic model?

My answer would be no, but the model poses challenges that will sharpen our understanding of dopamine and learning.

By Naoshige Uchida
13 September 2024 | 8 min read
Illustration of a series of squares containing distinct patterns.

Can an emerging field called ‘neural systems understanding’ explain the brain?

This mashup of neuroscience, artificial intelligence and even linguistics and philosophy of mind aims to crack the deep question of what "understanding" is, however un-brain-like its models may be.

By George Musser
5 June 2024 | 21 min listen

Dancing in the dark: Honeybees use antennae to decode nestmates’ waggles

The insects align their antennae with their body’s angle to a dancer—information that vector-processing circuitry in the brain deciphers into a flight path, a new study suggests.

By Shaena Montanari
3 April 2024 | 0 min watch
A photograph of a crab

In hot water: Climate change tests limits of neuronal resilience in crabs

Warming seas disrupt the function of neurons — and could seed permanent changes in marine species, according to studies of a circuit that controls digestion in crustaceans.

By Angie Voyles Askham
12 February 2024 | 7 min read

Explore more from The Transmitter

Research image of fMRI scans showing decision-making across individuals.

During decision-making, brain shows multiple distinct subtypes of activity

Person-to-person variability in brain activity might represent meaningful differences in cognitive processes, rather than random noise.

By Claudia López Lloreda
18 April 2025 | 5 min read
National Institutes of Health building cleaved in two.

Proposed NIH budget cut threatens ‘massive destruction of American science’

A leaked draft of a Trump administration proposal includes an approximately 40 percent cut to the National Institutes of Health’s budget and a major reorganization of its 27 institutes and centers.

By Angie Voyles Askham
17 April 2025 | 3 min read
Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read