Modeling
Recent articles
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
Not playing around: Why neuroscience needs toy models
Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.
Not playing around: Why neuroscience needs toy models
Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
Explore more from The Transmitter
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
Highlights from the first-ever Neural Genetics and Epigenetics Gordon Research Conference
The meeting’s organizers recap the science to watch.
Highlights from the first-ever Neural Genetics and Epigenetics Gordon Research Conference
The meeting’s organizers recap the science to watch.
Cortical territories compete in developmental space race
Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.
Cortical territories compete in developmental space race
Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.