Modeling
Recent articles
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Gabriele Scheler reflects on the interplay between language, thought and AI
She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.
Gabriele Scheler reflects on the interplay between language, thought and AI
She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.
How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.
How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Reconstructing dopamine’s link to reward
The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.
Dopamine and the need for alternative theories
Some experimental findings are inconsistent with the dominant model of reward prediction error, highlighting the need for alternative testable and falsifiable models for dopamine function.
Dopamine and the need for alternative theories
Some experimental findings are inconsistent with the dominant model of reward prediction error, highlighting the need for alternative testable and falsifiable models for dopamine function.
Does a new theory of dopamine replace the classic model?
My answer would be no, but the model poses challenges that will sharpen our understanding of dopamine and learning.
Does a new theory of dopamine replace the classic model?
My answer would be no, but the model poses challenges that will sharpen our understanding of dopamine and learning.
Explore more from The Transmitter
NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.
NIH proposal sows concerns over future of animal research, unnecessary costs
The new NIH policy calls for greater incorporation of new approach methodologies in all future Notices of Funding Opportunities related to animal model systems.
Altered transcription in dup15q syndrome; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 14 July.
Altered transcription in dup15q syndrome; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 14 July.
Fear and loathing on study section: Reviewing grant proposals while the system is burning
As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.
Fear and loathing on study section: Reviewing grant proposals while the system is burning
As grants are canceled, delayed and subject to general uncertainty, participating in study sections can feel futile. But it’s more important than ever.