Mitochondria

Recent articles

Research image of mitochondrial activity in the mouse amygdala and hippocampus.

The fast-expanding repertoire of mitochondria in the brain

More than cellular powerhouses, these organelles also seem to help synapses communicate, support memory formation and even shape behavior.

By Giorgia Guglielmi
3 July 2026 | 7 min read
Research image of zebrafish brain activity.

Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish

Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.

By Charles Q. Choi
16 April 2026 | 4 min read
Mouse sensory neurons express the ion channel TPRV1 .

Neurons tune electron transport chain to survive onslaught of noxious stimuli

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

By Viviane Callier
22 October 2025 | 5 min read
Eraser sitting on a stack of papers.

Alzheimer’s paper retracted over apparent image duplication

The editors of Neurobiology of Disease, which published the paper, also questioned how the study’s experimental protocols received ethical approval.

By Lauren Schneider
23 September 2025 | 4 min read
Sleep-control neurons glow cyan in the central nervous system of a fly.

Mitochondria set ‘ancient’ metabolic thermostat for sleep in flies, separate from circadian rhythms

During waking hours, a specialized set of sleep neurons in the fly brain accumulates reactive oxygen species, which eventually trigger sleep to clean up and repair the damage they do.

By Viviane Callier
9 September 2025 | 5 min read
Pixelated human brain scans showing the distribution of mitochondria.

Mitochondrial ‘landscape’ shifts across human brain

Evolutionarily newer regions sport mitochondria with a higher capacity for energy production than older regions, according to the first detailed map of the organelles in a tissue slice, adding to mounting evidence that the brain features a metabolic gradient.

By Claudia López Lloreda
25 April 2025 | 6 min read
Illustration of mitochondria as a kind of Stonehenge, with the shapes standing upright, casting shadows, against a blue sky.

Mitochondria mediate effects of PTEN mutations

Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.

By Katie Moisse
26 June 2023 | 4 min read
lllustration of the junction between two nerve cells.

Multi-omics study captures CNTNAP2’s far-ranging effects

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

By Charles Q. Choi
8 December 2022 | 4 min read

Unlocking the mitochondrial genome for autism research

The DNA specific to mitochondria is difficult to access, but new methods place its secrets within reach.

By Laura Dattaro
1 June 2022 | 5 min read

Mitochondria: An energy explanation for autism

People with autism have more mutations than others do in both mitochondrial DNA and nuclear DNA that affects mitochondrial function.

By Laura Dattaro
22 November 2021 | 1 min read

Explore more from The Transmitter

Research image of mouse and human Purkinje cells.

Purkinje cells evolved to have increasingly complex architecture

An increasing proportion of the cerebellar neurons acquired multiple primary dendrites in humans and other apes, according to a comparison of 11 primate species.

By Siddhant Pusdekar
16 July 2026 | 5 min read
Research image of mouse brain.

Making waves: Sleep-like brain activity in awake mice lowers sleep need, boosts memory

Alternating on/off firing patterns don’t just characterize deep, slow-wave sleep, they drive some of its restorative benefits, new findings suggest.

By Alissa de Chassey
16 July 2026 | 4 min read