Microbiome

Recent articles

Illustration of a body, brain visible through a transparent head, looking at orange circles over its hands.

Rethinking mental health: The body’s impact on the brain

Mounting evidence illustrates how peripheral molecules can influence brain function, offering new therapeutic targets.

By Georgia E. Hodes
11 February 2025 | 6 min read
A photograph of researcher Aya Osman

Striking a pose with Aya Osman

The neuroscientist and part-time fashion model opens up about the people who inspire her; her interest in science communication; and how she once ended up on a stage with Channing Tatum.

By Angie Voyles Askham
31 May 2024 | 7 min read
Research image of microglia in rats.

Temperament is innate but hackable, animal studies suggest

Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.

By Holly Barker
23 January 2024 | 8 min read
Digital illustration of Prevotella bacteria.

Gut microbiome meta-analysis reveals consistent autism signal

But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.

By Calli McMurray
22 August 2023 | 5 min read

‘wildDISCO’ cocktail yields whole-body maps of mouse neurons and more

A new technique used to create see-through rodents can help scientists analyze how the nervous system interacts with other body systems.

By Charles Q. Choi
20 July 2023 | 4 min read
Illustration of a pregnant woman seated next to a large diagram of the brain featuring chromosomes, bacteria and other microbes.

The link between maternal infection and autism, explained

Having an infection during pregnancy is tied to a small increase in the chances of having an autistic child, but the connection may not be causal.

By Charles Q. Choi
13 December 2022 | 7 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: COVID-19 conclusions; diagnosis duplication; oxytocin again

This month’s newsletter explores the pandemic’s effects on autism rates, trends in co-occurring mental health conditions, and the impact of intranasal oxytocin.

By Emily Harris
10 November 2022 | 5 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Medication timing; oxytocin amounts; sensory sameness

Parents’ health, treatment dosages and sensory perception feature in this month’s crop of null and replicated results.

By Emily Harris
13 October 2022 | 5 min read

Gut molecule linked to decreased myelination in mouse brains

Targeting the molecule, 4EPS, with an experimental drug may be a way to ease anxiety for autistic people, the researchers say. But not everyone is convinced.

By Angie Voyles Askham
14 February 2022 | 6 min read
Micrograph of intestinal bacteria.

Infection in pregnant mice ups risk of gut problems in pups

Infection during pregnancy can tweak a mouse’s gut microbiome in ways that have lasting effects on her pups’ immune system and increase their chances of gut inflammation, a new study suggests.

By Angie Voyles Askham
18 January 2022 | 5 min read

Explore more from The Transmitter

dendritic spine images

Targeting NMDA receptor subunit reverses fragile X traits in mice

The subunit acts as a “volume control” on signaling that shapes the density of dendritic spines, the new work suggests.

By Angie Voyles Askham
6 March 2025 | 5 min read
A pregnant woman seen in profile, sitting on the edge of a bed.

Maternal infection’s link to autism may be a mirage

Family-linked factors explain most associations between maternal illness and autism, a study of 1.1 million Danish children finds.

By Charles Q. Choi
6 March 2025 | 3 min read
Headshots of Michelle Monje and Frank Winkler.

2025 Brain Prize honors pair of cancer neuroscientists

Michelle Monje and Frank Winkler share the $1.4 million award for their discovery of synapses between brain cancer cells and neurons.

By Sydney Wyatt
5 March 2025 | 3 min read