Methods
Recent articles
Imagining the ultimate systems neuroscience paper
A growing body of papers on systems neuroscience and on giant simulations of neural circuits involves data beyond the point that anyone can reasonably understand end to end. Looking ahead, “paper-bots” could solve that problem.
Imagining the ultimate systems neuroscience paper
A growing body of papers on systems neuroscience and on giant simulations of neural circuits involves data beyond the point that anyone can reasonably understand end to end. Looking ahead, “paper-bots” could solve that problem.
To keep or not to keep: Neurophysiology’s data dilemma
An exponential growth in data size presents neuroscientists with a significant challenge: Should we be keeping all raw data or focusing on processed datasets? I asked experimentalists and theorists for their thoughts.
To keep or not to keep: Neurophysiology’s data dilemma
An exponential growth in data size presents neuroscientists with a significant challenge: Should we be keeping all raw data or focusing on processed datasets? I asked experimentalists and theorists for their thoughts.
Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
Expanding set of viral tools targets almost any brain cell type
Harmless viruses that encase short noncoding DNA elements called enhancers enable cell-type-specific gene delivery across the central nervous system in rodents and primates.
Mouse housing temperatures can cook experimental outcomes
Neuroscientists need to take note of how thermoregulatory processes influence the brain and behavior—for the sake of reproducibility and animal welfare.
Mouse housing temperatures can cook experimental outcomes
Neuroscientists need to take note of how thermoregulatory processes influence the brain and behavior—for the sake of reproducibility and animal welfare.
Electrical fingerprints track single neurons over several months
The new approach, called UnitMatch, improves on past methods for analyzing large electrophysiological datasets, the researchers say.
Electrical fingerprints track single neurons over several months
The new approach, called UnitMatch, improves on past methods for analyzing large electrophysiological datasets, the researchers say.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
Brains, biases and amyloid beta: Why the female brain deserves a closer look in Alzheimer’s research
New results suggest the disease progresses differently in women, but we need more basic science to unpack the mechanisms involved.
New tissue-clearing techniques let microscopes peer deeper into living brains
Washing mouse brain tissue with a blood protein or complex sugar can illuminate cells 550 micrometers into the cortex without compromising its normal physiology.
New tissue-clearing techniques let microscopes peer deeper into living brains
Washing mouse brain tissue with a blood protein or complex sugar can illuminate cells 550 micrometers into the cortex without compromising its normal physiology.
The S-index Challenge: Develop a metric to quantify data-sharing success
The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.
The S-index Challenge: Develop a metric to quantify data-sharing success
The NIH-sponsored effort aims to help incentivize scientists to share data. But many barriers to the widespread adoption of useful data-sharing remain.
Explore more from The Transmitter
Anti-seizure medications in pregnancy; TBR1 gene; microglia
Here is a roundup of autism-related news and research spotted around the web for the week of 2 December.
Anti-seizure medications in pregnancy; TBR1 gene; microglia
Here is a roundup of autism-related news and research spotted around the web for the week of 2 December.
Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain
The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.
Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain
The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.
This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.
This paper changed my life: ‘Histone demethylation mediated by the nuclear amine oxidase homolog LSD1,’ from the Shi Lab
This paper defined key rules of epigenomic regulation and shaped how I study chromatin plasticity as a mechanism for experience-dependent changes in the brain.