Methods
Recent articles
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.

Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
How tiny tardigrades could help tackle systems neuroscience questions
The eight-legged, millimeter-long animals reveal how small nervous systems produce complex behaviors and perceptual abilities, a preprint suggests.

How tiny tardigrades could help tackle systems neuroscience questions
The eight-legged, millimeter-long animals reveal how small nervous systems produce complex behaviors and perceptual abilities, a preprint suggests.
The limits of neuroscience
Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.

The limits of neuroscience
Truly understanding the brain requires a set of conditions we’re unlikely to meet: that knowledge about the brain is finite, and that we have both access to that knowledge and the means to understand it.
Breaking the barrier between theorists and experimentalists
Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments toward deeper insights.

Breaking the barrier between theorists and experimentalists
Many neuroscience students are steeped in an experiment-first style of thinking that leads to “random walk science.” Let’s not forget how theory can guide experiments toward deeper insights.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Plaque levels differ in popular Alzheimer’s mouse model depending on which parent’s variants are passed down
5XFAD model mice that inherit two disease-related genes from their fathers have double the plaques seen in those with maternal inheritance, a new study shows.
Protocol-sharing site aims to ease administrative burden of animal research
The library of regulatory-compliant animal procedures offers experimental standards and specific language that researchers can borrow for their own legal paperwork.

Protocol-sharing site aims to ease administrative burden of animal research
The library of regulatory-compliant animal procedures offers experimental standards and specific language that researchers can borrow for their own legal paperwork.
Digitization of ‘breathtaking’ neuroanatomy slide collection offers untapped research gold mine
Thousands of histological sections of vertebrate brains—including from spiny dogfish, turtles and more—are newly available online.

Digitization of ‘breathtaking’ neuroanatomy slide collection offers untapped research gold mine
Thousands of histological sections of vertebrate brains—including from spiny dogfish, turtles and more—are newly available online.
David Krakauer reflects on the foundations and future of complexity science
In his book “The Complex World,” Krakauer explores how complexity science developed, from its early roots to the four pillars that now define it—entropy, evolution, dynamics and computation.
David Krakauer reflects on the foundations and future of complexity science
In his book “The Complex World,” Krakauer explores how complexity science developed, from its early roots to the four pillars that now define it—entropy, evolution, dynamics and computation.
Spectrum 2024: Year in review
We round up our most notable autism stories of the past 12 months.

Spectrum 2024: Year in review
We round up our most notable autism stories of the past 12 months.
Explore more from The Transmitter
NIH neurodevelopmental assessment system now available as iPad app
Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.

NIH neurodevelopmental assessment system now available as iPad app
Here is a roundup of autism-related news and research spotted around the web for the week of 24 March.
Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor
Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.

Keep sex as a biological variable: Don’t let NIH upheaval turn back the clock on scientific rigor
Even in the absence of any formal instruction to do so, we should continue to hold our ourselves and our neuroscience colleagues accountable for SABV practices.
Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.

Single-cell genomics technologies and cell atlases have ushered in a new era of human neurobiology
Single-cell approaches are already shedding light on the human brain, identifying cell types that are most vulnerable in the early stages of Alzheimer’s disease, for example.