MECP2
Recent articles
Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.

Parasite-based tool delivers MECP2 and other proteins to neurons
A method that uses a common brain parasite could help replenish the proteins deficient in Rett syndrome and other conditions.
Autism-linked genes shape touch processing through different mechanisms, at different times
Whereas some mice display hypersensitivity to touch only as adults, others respond that way from birth.
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Autism-linked genes shape touch processing through different mechanisms, at different times
Whereas some mice display hypersensitivity to touch only as adults, others respond that way from birth.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
On the periphery: Thinking ‘outside the brain’ offers new ideas about autism
Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.
FDA approval of trofinetide may spur further drug development for Rett
The drug, welcomed by patients, might be just the first of many.
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FDA approval of trofinetide may spur further drug development for Rett
The drug, welcomed by patients, might be just the first of many.
Debut drug for Rett syndrome at edge of approval
The U.S. Food and Drug Administration plans to make an approval decision on the first-ever drug for girls and women with Rett syndrome by 12 March.
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Debut drug for Rett syndrome at edge of approval
The U.S. Food and Drug Administration plans to make an approval decision on the first-ever drug for girls and women with Rett syndrome by 12 March.
Going on Trial: Orphan drugs; CBD; bumetanide
This month’s newsletter takes a close look at the orphan drug program in the United States, several cannabis-based therapies and a secondary analysis of bumetanide, among other new developments in autism-related drug trials.
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Going on Trial: Orphan drugs; CBD; bumetanide
This month’s newsletter takes a close look at the orphan drug program in the United States, several cannabis-based therapies and a secondary analysis of bumetanide, among other new developments in autism-related drug trials.
Epigenome edits unmute MECP2 in Rett-like neurons
The approach removes methyl tags from the gene and shields it from other silencing factors without changing the gene itself, raising hopes for a new treatment.
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Epigenome edits unmute MECP2 in Rett-like neurons
The approach removes methyl tags from the gene and shields it from other silencing factors without changing the gene itself, raising hopes for a new treatment.
RNA rewrite improves breathing, survival in Rett mice
The technique involves editing the cellular instructions to make MECP2 protein and partially restores its levels in the brainstem.
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RNA rewrite improves breathing, survival in Rett mice
The technique involves editing the cellular instructions to make MECP2 protein and partially restores its levels in the brainstem.
Portrait of a research field: astrocytes in autism
Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Portrait of a research field: astrocytes in autism
Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Faulty inhibition foils long-term memory in Rett mice
The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.
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Faulty inhibition foils long-term memory in Rett mice
The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.
Explore more from The Transmitter
‘Spoonful of plastics in your brain’ paper has duplicated images
The duplications likely do not alter the conclusions, but the paper contains other methodological issues, two independent microplastics researchers say.
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‘Spoonful of plastics in your brain’ paper has duplicated images
The duplications likely do not alter the conclusions, but the paper contains other methodological issues, two independent microplastics researchers say.
The last two-author neuroscience paper?
Author lists on papers have ballooned, and it’s getting hard to discern contribution.
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The last two-author neuroscience paper?
Author lists on papers have ballooned, and it’s getting hard to discern contribution.
Attention and IQ link; AUTS2-related syndrome; Glyx-13 for fragile X
Here is a roundup of autism-related news and research spotted around the web for the week of 24 February.
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Attention and IQ link; AUTS2-related syndrome; Glyx-13 for fragile X
Here is a roundup of autism-related news and research spotted around the web for the week of 24 February.