Ion channels

Recent articles

How energy determines where proteins are produced in neurons

Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.

By Gaute Einevoll
26 August 2026 | 104 min listen
Annette Dolphin.

Remembering Annette Dolphin, who helped explain gabapentin’s effects

The "intuitive" neuropharmacologist pushed against the status quo.

By Michael Eisenstein
13 March 2026 | 7 min read
Stack of papers.

What are the most-cited neuroscience papers from the past 30 years?

Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.

By The Transmitter
15 November 2025 | 11 min read
Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
Photograph of Theanne Griffith sitting at a table with her hands interlocked over a stack of books, with one that she has published at the very top.

Crafting tales of science with Theanne Griffith

A lifelong passion for writing helped the neuroscientist land a book deal and publish 15 chapter books for early readers, covering topics ranging from what the cerebellum does to how a cake bakes.

By Angie Voyles Askham
26 August 2024 | 8 min read
Research image of two fluorescent-stained organoids.

CRISPR gives autism-linked genes a boost, rescues functioning

A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.

By Giorgia Guglielmi
23 May 2024 | 5 min read
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
Black-and-white photograph of William Catterall in a lab.

The legacy of William Catterall, ‘father of ion channels’

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

By Calli McMurray
12 March 2024 | 7 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read
Figure shows cultured human kidney cells and cultured rat cortical neurons responding to light exposure.

Unconventional optogenetics technique spurs long-lasting changes in neuronal activity

Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.

By Peter Hess
9 January 2023 | 4 min read

Explore more from The Transmitter

Illustration of a bridge shaped like minds.

Commentary: Citation graphs may underestimate neuroscience’s influence on AI

An alternative, albeit less quantitative, way to trace this history is through the people who carried ideas between the fields.

By Anthony Zador
26 October 2026 | 5 min read
Illustration of a person, shown from the torso down, walking over a bridge shaped like minds.

Commentary: The rising absolute number of neuro-inspired AI papers represents a substantial footprint

Many of the design choices present in the current generation of artificial-intelligence tools parallel purported properties of the brain.

By Kim Stachenfeld
26 October 2026 | 2 min read
Illustration of a person walking over a bridge shaped like minds.

Examining the bridge between neuroscience and AI

A citation analysis reveals that the connection between the two fields is real and gaining momentum. But it’s also narrow and tool-heavy; we need to find ways to widen it.

By Renato Duarte
26 October 2026 | 12 min read