Ion channels
Recent articles
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
Remembering Annette Dolphin, who helped explain gabapentin’s effects
The "intuitive" neuropharmacologist pushed against the status quo.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.
What are the most-cited neuroscience papers from the past 30 years?
Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.
Ketamine targets lateral habenula, setting off cascade of antidepressant effects
The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.
Crafting tales of science with Theanne Griffith
A lifelong passion for writing helped the neuroscientist land a book deal and publish 15 chapter books for early readers, covering topics ranging from what the cerebellum does to how a cake bakes.
Crafting tales of science with Theanne Griffith
A lifelong passion for writing helped the neuroscientist land a book deal and publish 15 chapter books for early readers, covering topics ranging from what the cerebellum does to how a cake bakes.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
The legacy of William Catterall, ‘father of ion channels’
Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.
The legacy of William Catterall, ‘father of ion channels’
Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Top autism-linked genes join forces to shape synaptic plasticity
The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.
Unconventional optogenetics technique spurs long-lasting changes in neuronal activity
Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.
Unconventional optogenetics technique spurs long-lasting changes in neuronal activity
Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.
Explore more from The Transmitter
What to do when traditional mechanistic approaches no longer work
Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”
What to do when traditional mechanistic approaches no longer work
Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”
University probe leads to retraction of four neural tube studies
The University of Maryland conducted an internal investigation that identified image duplications and other data integrity issues in the studies, according to the retraction notices.
University probe leads to retraction of four neural tube studies
The University of Maryland conducted an internal investigation that identified image duplications and other data integrity issues in the studies, according to the retraction notices.
Highly cited autism paper earns expression of concern over data duplications
The notice, published in Nature last week, also addressed an image duplication identified by a prominent research-integrity sleuth.
Highly cited autism paper earns expression of concern over data duplications
The notice, published in Nature last week, also addressed an image duplication identified by a prominent research-integrity sleuth.