Intellectual disability
Recent articles
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
New organoid atlas unveils four neurodevelopmental signatures
The comprehensive resource details data on microcephaly, polymicrogyria, epilepsy and intellectual disability from 352 people.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
Gene replacement therapy normalizes some traits in SYNGAP1 model mice
The first published virus-based gene therapy for SYNGAP1 deletion yields benefits despite the gene’s long length and complexity.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Expediting clinical trials for profound autism: Q&A with Matthew State
Aligning Research to Impact Autism, a new initiative funded by the Sergey Brin Family Foundation, wants to bring basic science discoveries to the clinic faster.
Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.
Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions
Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.
New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.
New catalog charts familial ties from autism to 90 other conditions
The research tool reveals associations stretching across three generations.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel
A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.
Autism-linked perturbations converge on cell skeleton and RNA-binding proteins
The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.
SYNGAP1 findings illuminate links between mutations, intellectual disability
New mouse models join several studies that could point to novel therapeutic approaches.
SYNGAP1 findings illuminate links between mutations, intellectual disability
New mouse models join several studies that could point to novel therapeutic approaches.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Autism research hits the road
Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.
Explore more from The Transmitter
AI can’t solve the brain without data that fit together
The brain's first foundation models exist because some areas of neuroscience did the slow work of developing and adopting standards to help integrate data. Artificial intelligence cannot do that work for us.
AI can’t solve the brain without data that fit together
The brain's first foundation models exist because some areas of neuroscience did the slow work of developing and adopting standards to help integrate data. Artificial intelligence cannot do that work for us.
Queerying neuroscience: How legislation and institutions reframe LGBTQIA+ researchers’ careers
In honor of Pride Month, The Transmitter spoke with three researchers who surveyed hundreds of LGBTQIA+ neuroscientists to better understand how institutional support, harassment and policy intersect to shape their professional trajectories.
Queerying neuroscience: How legislation and institutions reframe LGBTQIA+ researchers’ careers
In honor of Pride Month, The Transmitter spoke with three researchers who surveyed hundreds of LGBTQIA+ neuroscientists to better understand how institutional support, harassment and policy intersect to shape their professional trajectories.
Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion
The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.
Remembering Avis H. Cohen, who bridged disciplines to decode lamprey locomotion
The founding director of the University of Maryland’s Neuroscience and Cognitive Science program brought neuroscience, math and engineering together.