Intellectual disability

Recent articles

Research image of brain scans.

Impaired molecular ‘chaperone’ accompanies multiple brain changes, conditions

Rare genetic variants in a protein-folding complex contribute to a spectrum of phenotypes that encompass brain malformations, intellectual disability, autism and seizures, according to a new “hallmark” study.

By Holly Barker
12 December 2024 | 5 min read
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read
Portrait of Matthew Siegel sitting on a staircase.

Pinning down ‘profound autism’ for reliable research: Q&A with Matthew Siegel

A clear and actionable definition for the term could enhance research and improve care, Matthew Siegel says.

By Katie Moisse
13 June 2024 | 7 min read
A research image of autism-linked genes.

Autism-linked perturbations converge on cell skeleton and RNA-binding proteins

The findings solidify the idea that autism-linked mutations affect brain activity by way of several key shared mechanisms.

By Giorgia Guglielmi
29 February 2024 | 4 min read
Image of a synapse firing.

SYNGAP1 findings illuminate links between mutations, intellectual disability

New mouse models join several studies that could point to novel therapeutic approaches.

By Claudia López Lloreda
21 December 2023 | 6 min read

Autism research hits the road

Some scientists are thinking creatively about how to collect data in flexible environments and meet communities where they’re at.

By Giorgia Guglielmi
8 December 2023 | 0 min watch
A group of elementary school children run toward the entrance of a school, their backs turned to the camera.

Journal club: Why do some children lose their autism diagnosis?

More than one-third of a cohort of autistic toddlers no longer meet criteria for the condition at school age, according to a new study, but the findings may not generalize because the cohort is predominantly white and affluent.

By Deborah Fein
9 October 2023 | 6 min listen
Black-and-white illustrated portrait of Jonathan Green.

‘Emergent and transactional’: How Jonathan Green is rethinking autism and interventions

The experienced clinician discusses writing his recent paper, and its reception in the field.

By Brady Huggett
28 August 2023 | 1 min read
Blurry photograph of a crowd of people on a street.

Some who lack autism diagnosis carry variants tied to the condition

The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.

By Charles Q. Choi
13 July 2023 | 4 min read

Explore more from The Transmitter

Stimulating the brain with Damien Fair

The MacArthur Foundation “genius” discusses his return to his home state of Minnesota and why it’s important to protect the developing brain.

By Brady Huggett
3 February 2025 | 68 min listen

Roundup: The false association between vaccines and autism

In light of Robert F. Kennedy Jr.’s U.S. Senate confirmation hearings this week, The Transmitter has rounded up our past coverage of the false association between vaccines and autism.

By The Transmitter
31 January 2025 | 1 min read

Static pay, shrinking prospects fuel neuroscience postdoc decline

Postdoctoral researchers sponsored by the National Institutes of Health now toil longer than ever before, for less money. They are responding accordingly.

By Katie Moisse
31 January 2025 | 20 min read